Gene: FUT10

84750
FUCTX
fucosyltransferase 10
protein-coding
8p12
Ensembl:ENSG00000172728 MIM:616931 Vega:OTTHUMG00000163954 UniprotKB:Q6P4F1
NC_000008.11
SNP Mapped
1   ANCO-SNPs
CD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
3.964e-1 (AD)  8.235e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs871355chr8:33357908 (GRCh38.p7)C>Tcocaine dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SLC7A110.865
ARHGEF260.862
SLC2A100.861
NOTCH20.851
PREX20.847
TRPS10.847
GPC50.844
GLI30.842
MCC0.841
ELOVL20.84

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
NRG1-0.464
CACNA1F-0.463
GALNT14-0.455
ADTRP-0.424
TRABD2A-0.421
NELL1-0.418
CYP26A1-0.417
TMEFF2-0.416
MCHR1-0.404
CIDEA-0.402

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
D000082AcetaminophenAcetaminophen results in decreased expression of FUT10 mRNA26690555
D000082AcetaminophenAcetaminophen affects the expression of FUT10 mRNA17562736
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased mutagenesis of FUT10 gene25435355
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of FUT10 mRNA22228805
C006780bisphenol Abisphenol A results in decreased expression of FUT10 mRNA25181051
C006780bisphenol Abisphenol A results in increased methylation of FUT10 gene28505145
C018475butyraldehydebutyraldehyde results in decreased expression of FUT10 mRNA26079696
D019327Copper SulfateCopper Sulfate results in decreased expression of FUT10 mRNA19549813
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in increased expression of FUT10 mRNA27392435
D002945CisplatinCisplatin results in increased expression of FUT10 mRNA27392435
C000944dicrotophosdicrotophos results in decreased expression of FUT10 mRNA28302478
D017313FenretinideFenretinide results in decreased expression of FUT10 mRNA28973697
C544151jinfukang[Cisplatin co-treated with jinfukang] results in increased expression of FUT10 mRNA27392435
D008558MelphalanMelphalan results in decreased expression of FUT10 mRNA22363485
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of FUT10 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in increased expression of FUT10 mRNA"20188158
C045362prochlorazprochloraz results in increased expression of FUT10 mRNA21470553
C513428pyrachlostrobinpyrachlostrobin results in increased expression of FUT10 mRNA27029645
C017947sodium arsenitesodium arsenite affects the expression of FUT10 mRNA29319823
D013629TamoxifenTamoxifen results in increased expression of FUT10 mRNA25123088
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of FUT10 mRNA21570461
D014635Valproic AcidValproic Acid results in decreased expression of FUT10 mRNA28001369
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of FUT10 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0046920alpha-(1->3)-fucosyltransferase activity-IBA21873635  
GO:0046920alpha-(1->3)-fucosyltransferase activity-TAS11698403  
GO ID GO Term Qualifier Evidence PubMed
GO:0006457protein folding-NAS11698403  
GO:0006486protein glycosylation-IEA-  
GO:0006486protein glycosylation-TAS11698403  
GO:0006605protein targeting-NAS11698403  
GO:0007399nervous system development-NAS11698403  
GO:0009566fertilization-NAS11698403  
GO:0021799cerebral cortex radially oriented cell migration-IEA-  
GO:0030097hemopoiesis-NAS11698403  
GO:0036065fucosylation-IBA21873635  
GO:0036065fucosylation-IEA-  
GO:0042060wound healing-NAS11698403  
GO:0042355L-fucose catabolic process-NAS11698403  
GO:0097150neuronal stem cell population maintenance-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005654nucleoplasm-IDA-  
GO:0005783endoplasmic reticulum-IDA-  
GO:0005794Golgi apparatus-IDA-  
GO:0005794Golgi apparatus-TAS11698403  
GO:0016021integral component of membrane-IEA-  
GO:0032580Golgi cisterna membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal