Gene: STARD13

90627
ARHGAP37|DLC2|GT650|LINC00464
StAR related lipid transfer domain containing 13
protein-coding
13q13.1-q13.2
Ensembl:ENSG00000133121 MIM:609866 Vega:OTTHUMG00000016708 UniprotKB:Q9Y3M8
NG_029752.2
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.054e-1 (AD)  7.437e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs642899chr13:33106717 (GRCh38.p7)T>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

Probe Locus(GRCh37) Gene Region p-val Trait PubMed ID
cg24469742chr13:33773155STARD132.380e-9Maternal smoking in pregnancy27040690

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
SMURF10.866
TRAPPC100.846
TLE40.843
UVRAG0.84
PPP2R2A0.838
NXPE30.827
SIK20.822
PSME40.821
NFASC0.818
ITSN20.818

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F29-0.448
OR4F5-0.446
KCNJ16-0.39
PON3-0.383
C16orf74-0.356
PON1-0.355
NXNL1-0.346
ASB4-0.339
RLBP1-0.337
SLC22A6-0.337

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0264861,2,5,6-dibenzanthracene"1,2,5,6-dibenzanthracene results in decreased expression of STARD13 mRNA"26377693
C0095054,4'-diaminodiphenylmethane"4,4'-diaminodiphenylmethane results in decreased expression of STARD13 mRNA"25380136
D000082AcetaminophenAcetaminophen results in decreased expression of STARD13 mRNA25704631
D000082AcetaminophenAcetaminophen affects the expression of STARD13 mRNA17562736
D020106AcrylamideAcrylamide results in decreased expression of STARD13 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in decreased methylation of STARD13 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of STARD13 mRNA27153756
C015001arsenitearsenite results in increased methylation of STARD13 promoter23974009
D017638Asbestos, Crocidolite"Asbestos, Crocidolite results in increased expression of STARD13 mRNA"18687144
D001564Benzo(a)pyreneBenzo(a)pyrene results in decreased expression of STARD13 mRNA22316170
D004958Estradiol[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of STARD13 mRNA19619570
D004958EstradiolEstradiol results in increased expression of STARD13 mRNA19619570
C006780bisphenol Abisphenol A results in decreased expression of STARD13 mRNA29275510
C006780bisphenol Abisphenol A results in increased expression of STARD13 mRNA25594700
C006780bisphenol Abisphenol A results in decreased expression of STARD13 mRNA28196854
C006780bisphenol Abisphenol A results in decreased expression of STARD13 mRNA25181051
C018475butyraldehydebutyraldehyde results in decreased expression of STARD13 mRNA26079696
D019256Cadmium ChlorideCadmium Chloride affects the methylation of STARD13 promoter22457795
D002220CarbamazepineCarbamazepine affects the expression of STARD13 mRNA25979313
D007631ChlordeconeSTARD13 gene SNP affects the susceptibility to Chlordecone25622337
D002794Choline[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of STARD13 mRNA20938992
D002922CiguatoxinsCiguatoxins affects the expression of STARD13 mRNA18353800
C018021cobaltous chloridecobaltous chloride results in decreased expression of STARD13 mRNA24386269
D019327Copper SulfateCopper Sulfate results in decreased expression of STARD13 mRNA19549813
D016572CyclosporineCyclosporine results in decreased expression of STARD13 mRNA25562108|2798913
D002945Cisplatin[Cisplatin co-treated with jinfukang] results in decreased expression of STARD13 mRNA27392435
D002945CisplatinCisplatin results in decreased expression of STARD13 mRNA27392435|2759478
C015835dimethyl-4-toluidinedimethyl-4-toluidine results in decreased expression of STARD13 mRNA27638505
D004128DimethylnitrosamineDimethylnitrosamine results in decreased expression of STARD13 mRNA25380136
C045651epigallocatechin gallate[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of STARD13 mRNA22079256
D005492Folic Acid[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of STARD13 mRNA20938992
D005557FormaldehydeFormaldehyde results in decreased expression of STARD13 mRNA23416264
C039281furanfuran results in decreased expression of STARD13 mRNA25539665|2619464
D019833GenisteinGenistein results in decreased methylation of STARD13 gene28505145
D006861Hydrogen PeroxideHydrogen Peroxide affects the expression of STARD13 mRNA20044591
D015759Ionomycin[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of STARD13 mRNA25613284
C544151jinfukang[Cisplatin co-treated with jinfukang] results in decreased expression of STARD13 mRNA27392435
C544151jinfukangjinfukang results in decreased expression of STARD13 mRNA27392435
C045463leflunomideleflunomide results in increased expression of STARD13 mRNA28988120
D008715Methionine[Methionine deficiency co-treated with Choline deficiency co-treated with Folic Acid deficiency] results in decreased expression of STARD13 mRNA20938992
D008748MethylcholanthreneMethylcholanthrene promotes the reaction [AHR protein binds to STARD13 promoter]20348232
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of STARD13 mRNA23649840
D018817N-Methyl-3,4-methylenedioxyamphetamine"N-Methyl-3,4-methylenedioxyamphetamine results in decreased expression of STARD13 mRNA"26251327
C523799MRK 003STARD13 results in increased susceptibility to MRK 00319903844
C583365N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide"N-(2-(1,1'-bicyclopropyl)-2-ylphenyl)-3-(difluoromethyl)-1-methyl-1H-pyrazole-4-carboxamide results in decreased expression of STARD13 mRNA"29244179
D037742Nanotubes, Carbon"Nanotubes, Carbon analog results in decreased expression of STARD13 mRNA"25554681
D037742Nanotubes, Carbon"Nanotubes, Carbon results in decreased expression of STARD13 mRNA"25554681
D0150581-Naphthylisothiocyanate1-Naphthylisothiocyanate results in decreased expression of STARD13 mRNA25380136
C030110oxaliplatin[oxaliplatin co-treated with Topotecan] results in increased expression of STARD13 mRNA25729387
D010705PhosgenePhosgene affects the expression of STARD13 mRNA16300373
C027373potassium chromate(VI)[potassium chromate(VI) co-treated with epigallocatechin gallate] results in decreased expression of STARD13 mRNA22079256
C027373potassium chromate(VI)potassium chromate(VI) results in decreased expression of STARD13 mRNA22079256|2271453
D011441PropylthiouracilPropylthiouracil results in decreased expression of STARD13 mRNA24780913
C513428pyrachlostrobinpyrachlostrobin results in increased expression of STARD13 mRNA27029645
D011794QuercetinQuercetin results in decreased expression of STARD13 mRNA21632981
C513635S-2-pentyl-4-pentynoic hydroxamic acidS-2-pentyl-4-pentynoic hydroxamic acid results in increased expression of STARD13 mRNA21427059
D017632Asbestos, Serpentine"Asbestos, Serpentine results in increased expression of STARD13 mRNA"21148743
D012822Silicon DioxideSilicon Dioxide results in increased expression of STARD13 mRNA25351596
C016104sodium bichromatesodium bichromate affects the expression of STARD13 mRNA22110744
D018038Sodium SeleniteSodium Selenite results in decreased expression of STARD13 mRNA18175754
D013629TamoxifenTamoxifen affects the expression of STARD13 mRNA20937368
D013749Tetrachlorodibenzodioxin[Estradiol co-treated with Tetrachlorodibenzodioxin] results in increased expression of STARD13 mRNA19619570
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in decreased expression of STARD13 mRNA21296121
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin results in increased expression of STARD13 mRNA19619570|2010694
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of STARD13 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with TIPARP gene mutant form] results in increased expression of STARD13 mRNA25975270
D013755Tetradecanoylphorbol Acetate[Tetradecanoylphorbol Acetate co-treated with Ionomycin] results in decreased expression of STARD13 mRNA25613284
D019772Topotecan[oxaliplatin co-treated with Topotecan] results in increased expression of STARD13 mRNA25729387
D019772TopotecanTopotecan results in increased expression of STARD13 mRNA25729387
D014241TrichloroethyleneTrichloroethylene results in increased methylation of STARD13 gene27618143
C012589trichostatin Atrichostatin A results in increased expression of STARD13 mRNA24935251
C015559trimellitic anhydridetrimellitic anhydride results in decreased expression of STARD13 mRNA19042947
C016805tris(1,3-dichloro-2-propyl)phosphate"tris(1,3-dichloro-2-propyl)phosphate results in decreased expression of STARD13 mRNA"26179874
C013320tris(2-butoxyethyl) phosphatetris(2-butoxyethyl) phosphate affects the expression of STARD13 mRNA29024780
D014635Valproic AcidValproic Acid affects the expression of STARD13 mRNA25979313
D014635Valproic AcidValproic Acid results in increased expression of STARD13 mRNA24935251
D014635Valproic AcidValproic Acid results in increased expression of STARD13 mRNA21427059|2489608
D001335Vehicle EmissionsVehicle Emissions results in increased methylation of STARD13 gene25487561
D001335Vehicle EmissionsVehicle Emissions results in decreased methylation of STARD13 gene25560391
C025643vinclozolinvinclozolin results in increased expression of STARD13 mRNA23034163
C088658zoledronic acidzoledronic acid results in decreased expression of STARD13 mRNA24714768

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0005096GTPase activator activity-TAS-  
GO:0005515protein binding-IPI14697242  
GO:0008289lipid binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0007165signal transduction-IEA-  
GO:0043542endothelial cell migration-IGI20208559  
GO:0043542endothelial cell migration-IMP20208559  
GO:0043547positive regulation of GTPase activity-IEA-  
GO:0051056regulation of small GTPase mediated signal transduction-TAS-  
GO:0090051negative regulation of cell migration involved in sprouting angiogenesis-IGI20208559  
GO:0090051negative regulation of cell migration involved in sprouting angiogenesis-IMP20208559  
GO:0097498endothelial tube lumen extension-IGI20208559  
GO:0097498endothelial tube lumen extension-IMP20208559  
GO ID GO Term Qualifier Evidence PubMed
GO:0005811lipid droplet-IEA-  
GO:0005829cytosol-TAS-  
GO:0031966mitochondrial membrane-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-162582Signal TransductionTAS
R-HSA-194315Signaling by Rho GTPasesTAS
R-HSA-194840Rho GTPase cycleTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal