Gene: CTDP1

9150
CCFDN|FCP1
CTD phosphatase subunit 1
protein-coding
18q23
Ensembl:ENSG00000060069 MIM:604927 Vega:OTTHUMG00000132920 UniprotKB:Q9Y5B0
NG_007988.1
SNP Mapped
1   ANCO-SNPs
OD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
7.133e-1 (AD)  6.906e-2 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs74641711chr18:79727394 (GRCh38.p7)C>Topioid dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
XAB20.869
KIAA20130.866
ADRM10.863
AP5Z10.857
E2F40.852
SPNS10.846
ZGPAT0.846
DRG20.841
E4F10.84
HM130.836

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.584
OR4F29-0.541
MTRNR2L9-0.389
MTRNR2L6-0.361
MTRNR2L10-0.32
MTRNR2L1-0.276
OR4F16-0.268
MTRNR2L2-0.251
SFTA2-0.238
USP17L4-0.238

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C0164032,4-dinitrotoluene"2,4-dinitrotoluene affects the expression of CTDP1 mRNA"21346803
D000082AcetaminophenAcetaminophen results in decreased expression of CTDP1 mRNA22230336
D000082AcetaminophenAcetaminophen affects the expression of CTDP1 mRNA17562736
D020106AcrylamideAcrylamide results in increased expression of CTDP1 mRNA28959563
D016604Aflatoxin B1Aflatoxin B1 results in increased methylation of CTDP1 gene27153756
D016604Aflatoxin B1Aflatoxin B1 results in increased expression of CTDP1 mRNA19770486
D000535Aluminum[APP protein modified form binds to Aluminum] which results in decreased expression of CTDP1 mRNA21298039
D001151ArsenicArsenic affects the methylation of CTDP1 gene25304211
D001280AtrazineAtrazine results in increased expression of CTDP1 mRNA25929836
D001564Benzo(a)pyreneBenzo(a)pyrene results in increased expression of CTDP1 mRNA22228805
C006780bisphenol Abisphenol A results in decreased expression of CTDP1 mRNA25181051
D019256Cadmium ChlorideCadmium Chloride results in increased expression of CTDP1 mRNA19010381
D002251Carbon TetrachlorideCarbon Tetrachloride results in decreased expression of CTDP1 mRNA17484886
C059262cidofovircidofovir results in decreased expression of CTDP1 mRNA25596134
C012843cinnamic aldehydecinnamic aldehyde results in increased expression of CTDP1 mRNA20008804
D004002Clodronic AcidClodronic Acid results in decreased expression of CTDP1 mRNA25596134
C018021cobaltous chloridecobaltous chloride results in increased expression of CTDP1 mRNA19320972
C018021cobaltous chloridecobaltous chloride results in increased expression of CTDP1 mRNA24386269
D002945CisplatinCisplatin results in decreased expression of CTDP1 mRNA25596134
D004997Ethinyl EstradiolEthinyl Estradiol results in increased expression of CTDP1 mRNA17942748
D004997Ethinyl Estradiol[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTDP1 mRNA17942748
D006861Hydrogen PeroxideHydrogen Peroxide results in decreased expression of CTDP1 mRNA18951874
D007069IfosfamideIfosfamide results in decreased expression of CTDP1 mRNA25596134
D008687MetforminMetformin results in increased expression of CTDP1 mRNA25596134
D008741Methyl MethanesulfonateMethyl Methanesulfonate results in decreased expression of CTDP1 mRNA26011545
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of CTDP1 mRNA"12756304
D010100OxygenOxygen deficiency results in decreased expression of CTDP1 mRNA25596134
C006253pirinixic acid[pirinixic acid binds to and results in increased activity of PPARA protein] which results in increased expression of CTDP1 mRNA19710929
D012999SomanSoman results in increased expression of CTDP1 mRNA19281266
C004648testosterone enanthatetestosterone enanthate affects the expression of CTDP1 mRNA17440010
D013749TetrachlorodibenzodioxinTetrachlorodibenzodioxin affects the expression of CTDP1 mRNA21570461
D013749Tetrachlorodibenzodioxin[Tetrachlorodibenzodioxin co-treated with Ethinyl Estradiol] results in increased expression of CTDP1 mRNA17942748
D014241TrichloroethyleneTrichloroethylene results in increased methylation of CTDP1 gene27618143
C057693troglitazonetroglitazone results in decreased expression of CTDP1 mRNA28973697
D001335Vehicle EmissionsVehicle Emissions affects the methylation of CTDP1 gene25560391

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0001096TFIIF-class transcription factor binding-IPI12732728  15723517  
GO:0004721phosphoprotein phosphatase activity-TAS-  
GO:0005515protein binding-IPI9765293  15670829  
GO:0008420CTD phosphatase activity-IBA21873635  
GO:0008420CTD phosphatase activity-IDA9765293  12721286  
GO:0030957Tat protein binding-IPI15723517  
GO ID GO Term Qualifier Evidence PubMed
GO:0006366transcription by RNA polymerase II-TAS-  
GO:0006368transcription elongation from RNA polymerase II promoter-TAS-  
GO:0006470protein dephosphorylation-IDA9765293  22692537  
GO:0010458exit from mitosis-IMP22692537  
GO:0043923positive regulation by host of viral transcription-IDA15723517  
GO:0051301cell division-IEA-  
GO:0061052negative regulation of cell growth involved in cardiac muscle cell development-IEA-  
GO:0070940dephosphorylation of RNA polymerase II C-terminal domain-IBA21873635  
GO ID GO Term Qualifier Evidence PubMed
GO:0000922spindle pole-IDA22692537  
GO:0005634nucleus-IDA15723517  
GO:0005654nucleoplasm-IDA-  
GO:0005654nucleoplasm-TAS-  
GO:0005737cytoplasm-IEA-  
GO:0005813centrosome-IDA22692537  
GO:0005819spindle-IDA22692537  
GO:0016591DNA-directed RNA polymerase II, holoenzyme-IBA21873635  
GO:0030496midbody-IDA22692537  
GO:0032991protein-containing complex-IMP12732728  
GO:0043231intracellular membrane-bounded organelle-IDA-  
GO:0051233spindle midzone-IDA22692537  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-112382Formation of RNA Pol II elongation complex TAS
R-HSA-113418Formation of the Early Elongation ComplexTAS
R-HSA-162587HIV Life CycleIEA
R-HSA-162587HIV Life CycleTAS
R-HSA-162599Late Phase of HIV Life CycleIEA
R-HSA-162599Late Phase of HIV Life CycleTAS
R-HSA-162906HIV InfectionIEA
R-HSA-162906HIV InfectionTAS
R-HSA-1643685DiseaseIEA
R-HSA-1643685DiseaseTAS
R-HSA-167152Formation of HIV elongation complex in the absence of HIV TatIEA
R-HSA-167158Formation of the HIV-1 Early Elongation ComplexIEA
R-HSA-167169HIV Transcription ElongationIEA
R-HSA-167169HIV Transcription ElongationTAS
R-HSA-167172Transcription of the HIV genomeIEA
R-HSA-167172Transcription of the HIV genomeTAS
R-HSA-167200Formation of HIV-1 elongation complex containing HIV-1 TatIEA
R-HSA-167200Formation of HIV-1 elongation complex containing HIV-1 TatTAS
R-HSA-167238Pausing and recovery of Tat-mediated HIV elongationIEA
R-HSA-167242Abortive elongation of HIV-1 transcript in the absence of TatIEA
R-HSA-167243Tat-mediated HIV elongation arrest and recoveryIEA
R-HSA-167246Tat-mediated elongation of the HIV-1 transcriptIEA
R-HSA-167246Tat-mediated elongation of the HIV-1 transcriptTAS
R-HSA-167287HIV elongation arrest and recoveryIEA
R-HSA-167290Pausing and recovery of HIV elongationIEA
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-3700989Transcriptional Regulation by TP53TAS
R-HSA-5663205Infectious diseaseIEA
R-HSA-5663205Infectious diseaseTAS
R-HSA-674695RNA Polymerase II Pre-transcription EventsTAS
R-HSA-6796648TP53 Regulates Transcription of DNA Repair GenesTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS
R-HSA-75955RNA Polymerase II Transcription ElongationTAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal