Gene: ZNF764

92595
-
zinc finger protein 764
protein-coding
16p11.2
Ensembl:ENSG00000169951 Vega:OTTHUMG00000132406 UniprotKB:Q96H86
NC_000016.10
SNP Mapped
1   ANCO-SNPs
AD
0   
NA (AD)  NA (ND)   (Frontal_Cortex)
1.768e-3 (AD)  7.722e-1 (ND)

ANCO-SNPs

SNP ID Position Alleles Trait Variation Type
rs17790906chr16:30558338 (GRCh38.p7)T>Galcohol dependenceSNV(Single Nucleotide Variation)

DNA Methylation

There is no related methylation information for this gene.

Gene Expression in Different Tissues

Temporal and Spatial Expressions (BrainSpan)

Footnote:
SC: sub-cortical regions; SM: sensory-motor regions; FC: frontal cortex; and TP: temporal-parietal cortex
ST1: fetal (13 - 26 postconception weeks), ST2: early infancy to late childhood (4 months to 11 years), and ST3: adolescence to adulthood (13 - 23 years)
The bar shown representes average value of the expressions.

Top Co-expressed Genes in Brain-Frontal Cortex (BA9) (GTEx v7)

Top 10 positively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
ZNF4960.835
TNRC6C0.832
LRRC410.828
ALG120.826
ATP8B20.82
COG80.818
CNNM40.817
POM121C0.817
ZBED40.815
LIG30.815

Top 10 negatively co-expressed genes

Gene Symbol Pearson Correlation Coefficient
OR4F5-0.534
OR4F29-0.475
KLRC2-0.3
FMO3-0.266
HBD-0.262
CTNNA3-0.259
OR6C74-0.25
OR4F16-0.248
CSAG1-0.244
CPA3-0.243

Drugs/Compounds

    There is no DrugBank record for this gene !

ID Drug Name Action PubMed
C006780bisphenol Abisphenol A affects the expression of ZNF764 mRNA25181051
C018021cobaltous chloridecobaltous chloride results in increased expression of ZNF764 mRNA19376846
D016572CyclosporineCyclosporine results in decreased expression of ZNF764 mRNA25562108
C000944dicrotophosdicrotophos results in increased expression of ZNF764 mRNA28302478
D005557FormaldehydeFormaldehyde results in decreased expression of ZNF764 mRNA20655997
C004925methylmercuric chloridemethylmercuric chloride results in decreased expression of ZNF764 mRNA28001369
C044387N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine"N,N,N',N'-tetrakis(2-pyridylmethyl)ethylenediamine results in decreased expression of ZNF764 mRNA"12756304
D012822Silicon DioxideSilicon Dioxide results in increased expression of ZNF764 mRNA25351596
D014212TretinoinTretinoin results in decreased expression of ZNF764 mRNA23724009
D014520UrethaneUrethane results in decreased expression of ZNF764 mRNA28818685
D014635Valproic AcidValproic Acid affects the expression of ZNF764 mRNA25979313
D014635Valproic AcidValproic Acid results in decreased expression of ZNF764 mRNA28001369
D019287Zinc SulfateZinc Sulfate results in increased expression of ZNF764 mRNA12756304

GO/Pathway

GO ID GO Term Qualifier Evidence PubMed
GO:0000981RNA polymerase II transcription factor activity, sequence-specific DNA binding-ISA-  
GO:0003677DNA binding-IEA-  
GO:0005515protein binding-IPI16189514  
GO:0046872metal ion binding-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0006351transcription, DNA-templated-IEA-  
GO:0006357regulation of transcription by RNA polymerase II-IEA-  
GO ID GO Term Qualifier Evidence PubMed
GO:0005634nucleus-IEA-  
KEGG ID KEGG Term
Reactome ID Reactome Term Evidence
R-HSA-212436Generic Transcription PathwayTAS
R-HSA-73857RNA Polymerase II TranscriptionTAS
R-HSA-74160Gene expression (Transcription)TAS

Interactions (STRING v10.5, Interaction Score >= 0.400)

Publications (Co-occurrence of gene symbol strings and ANCO-Dependence terms)

PMID Title (Year) Author Journal