DegronMD

Uniprot ID: Q8IZF6

Source protein: Adhesion G-protein coupled receptor G4

Source gene: ADGRG4

Class: DEG_SPOP_SBC_1

Location: 264:268

E3 ligase: SPOP

DEGRON score: 0.8186

ASA_SCORE: 84.7

COIL: 0.8222

CONS_SCORE: 0.7838

DSS_SCORE: 0.4179

HELIX: 0.0722

FCONS_SCORE: 1.01

RIG_SCORE: 0.7364

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S277F	ML-1	thyroid	COSMIC	AHSST	DEG_SPOP_SBC_1	0.0833

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8IZF6	Adhesion G-protein coupled receptor G4	DEG_SPOP_SBC_1	264:268	AHSST	SPOP	0.8186	More...
P52740	Zinc finger protein 132	DEG_SPOP_SBC_1	553:557	AHSST	SPOP	0.5322	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons