DegronMD

Uniprot ID: B8ZZ34

Source protein: Protein shisa-8

Source gene: SHISA8

Class: DEG_SPOP_SBC_1

Location: 327:331

E3 ligase: SPOP

DEGRON score: 0.9837

ASA_SCORE: 80.02

COIL: 0.873

CONS_SCORE: 0

DSS_SCORE: 0.5008

HELIX: 0.0686

FCONS_SCORE: 0

RIG_SCORE: 0.6867

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.A320V	SIDM00628	Breast Carcinoma	GDSC	AWTSS	DEG_SPOP_SBC_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
B8ZZ34	Protein shisa-8	DEG_SPOP_SBC_1	327:331	AWTSS	SPOP	0.9837	More...
Q6NY19	KN motif and ankyrin repeat domain-containing protein 3	DEG_SPOP_SBC_1	88:92	AWTSS	SPOP	0.9992	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons