DegronMD

Uniprot ID: P61565

Source protein: Endogenous retrovirus group K member 21 Env polyprotein

Source gene: ERVK-21

Class: DEG_SIAH_1

Location: 281:289

E3 ligase: SIAH1,SIAH2,SIAH3

DEGRON score: 0.9623

ASA_SCORE: 50.1

COIL: 0.7961

CONS_SCORE: 0.2147

DSS_SCORE: 0.4727

HELIX: 0.1067

FCONS_SCORE: 1.3089

RIG_SCORE: 0.6755

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q69384	Endogenous retrovirus group K member 6 Env polyprotein	DEG_SIAH_1	282:290	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9623	More...
O71037	Endogenous retrovirus group K member 19 Env polyprotein	DEG_SIAH_1	282:290	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9551	More...
P61565	Endogenous retrovirus group K member 21 Env polyprotein	DEG_SIAH_1	281:289	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9623	More...
P61566	Endogenous retrovirus group K member 24 Env polyprotein	DEG_SIAH_1	171:179	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9511	More...
P61567	Endogenous retrovirus group K member 7 Env polyprotein	DEG_SIAH_1	171:179	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.7111	More...
Q902F8	Endogenous retrovirus group K member 8 Env polyprotein	DEG_SIAH_1	282:290	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9551	More...
Q902F9	Endogenous retrovirus group K member 113 Env polyprotein	DEG_SIAH_1	282:290	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.8831	More...
Q9UKH3	Endogenous retrovirus group K member 9 Env polyprotein	DEG_SIAH_1	281:289	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9581	More...
P61570	Endogenous retrovirus group K member 25 Env polyprotein	DEG_SIAH_1	282:290	CPSAQVSPA	SIAH1,SIAH2,SIAH3	0.9532	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons