DegronMD: protein-targeted degradation, mutation and drug response to degrons
Home
(current)
Browse
Proteins/Degrons
Mutations
Drug response
Network-rewiring
Drug resistance
Search
Tutorial
Download
Contact
Links
BSML
CPH
CGC
Degron:
DDKGAYSVGP
Uniprot ID:
P69849
Source protein:
Nodal modulator 3
Source gene:
NOMO3
Class:
CBL_PTK
Location:
833:842
E3 ligase:
CBL
DEGRON score:
0.6202
ASA_SCORE:
59.09
COIL:
0.6351
CONS_SCORE:
0.6097
DSS_SCORE:
0.2587
HELIX:
0.0092
FCONS_SCORE:
1.2515
RIG_SCORE:
0.7566
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with NOMO3 mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DDKGAYSVGP
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q15155
Nodal modulator 1
CBL_PTK
833:842
DDKGAYSVGP
CBL
0.7422
More...
Q5JPE7
Nodal modulator 2
CBL_PTK
833:842
DDKGAYSVGP
CBL
0.6202
More...
P69849
Nodal modulator 3
CBL_PTK
833:842
DDKGAYSVGP
CBL
0.6202
More...
