DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
DSGALT
Uniprot ID:
Q6ZRN7
Source protein:
Putative uncharacterized protein FLJ46214
Source gene:
-
Class:
DEG_SCF_TRCP1_1
Location:
26:31
E3 ligase:
BTRC
DEGRON score:
0.9455
ASA_SCORE:
85.8833
COIL:
0.9522
CONS_SCORE:
1
DSS_SCORE:
0.7605
HELIX:
0.0295
FCONS_SCORE:
1
RIG_SCORE:
0.5817
Degron related mutations and impact score
Mutation
Sample
Cancer
Dataset
Degron
Degron class
Impact score
Drug responses associated with - mutations
Sample
Cancer
Mutation (In Degron?)
Dataset
Drug
IC50
All proteins holding degron of DSGALT
Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q9NQ69
LIM/homeobox protein Lhx9
DEG_SCF_TRCP1_1
349:354
DSGALT
BTRC
0.9823
More...
Q6ZRN7
Putative uncharacterized protein FLJ46214
DEG_SCF_TRCP1_1
26:31
DSGALT
BTRC
0.9455
More...