DegronMD

Uniprot ID: Q8N350

Source protein: Voltage-dependent calcium channel beta subunit-associated regulatory protein

Source gene: CBARP

Class: DEG_SCF_TRCP1_1

Location: 185:191

E3 ligase: BTRC

DEGRON score: 0.9555

ASA_SCORE: 72.6

COIL: 0.8256

CONS_SCORE: 0.4645

DSS_SCORE: 0.5274

HELIX: 0.1204

FCONS_SCORE: 1.0004

RIG_SCORE: 0.6147

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.D185N	SIDM00153	T-Lymphoblastic Leukemia	GDSC	DSGEASS	DEG_SCF_TRCP1_1	0.6932

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q8N350	Voltage-dependent calcium channel beta subunit-associated regulatory protein	DEG_SCF_TRCP1_1	185:191	DSGEASS	BTRC	0.9555	More...
Q8TF21	Ankyrin repeat domain-containing protein 24	DEG_SCF_TRCP1_1	283:289	DSGEASS	BTRC	0.9713	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons