DegronMD

Uniprot ID: O95863

Source protein: Zinc finger protein SNAI1

Source gene: SNAI1

Class: DEG_SCF_TRCP1_1

Location: 95:100

E3 ligase: BTRC

DEGRON score: 0.9948

ASA_SCORE: 77.7

COIL: 0.9257

CONS_SCORE: 0.4855

DSS_SCORE: 0.7955

HELIX: 0.032

FCONS_SCORE: 1.0192

RIG_SCORE: 0.4781

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.P110S	TCGA-EB-A6QY	SKCM	TCGA	DSGKGS	DEG_SCF_TRCP1_1	0.0556
p.P110S	DO48702	SKCM	ICGC	DSGKGS	DEG_SCF_TRCP1_1	0.0556
p.L88M	DO232826	NACA	ICGC	DSGKGS	DEG_SCF_TRCP1_1	0.1389

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O95863	Zinc finger protein SNAI1	DEG_SCF_TRCP1_1	95:100	DSGKGS	BTRC	0.9948	More...
Q8IZD0	Sterile alpha motif domain-containing protein 14	DEG_SCF_TRCP1_1	243:248	DSGKGS	BTRC	0.9698	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons