DegronMD

Uniprot ID: Q9NUP1

Source protein: Biogenesis of lysosome-related organelles complex 1 subunit 4

Source gene: BLOC1S4

Class: DEG_SCF_TRCP1_1

Location: 29:34

E3 ligase: BTRC

DEGRON score: 0.6321

ASA_SCORE: 67.3167

COIL: 0.7607

CONS_SCORE: 0.2684

DSS_SCORE: 0.6961

HELIX: 0.0918

FCONS_SCORE: 0.9786

RIG_SCORE: 0.5765

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S36R	SIDM00364	B-Lymphoblastic Leukemia	GDSC	DSGTVS	DEG_SCF_TRCP1_1	0.2778

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
Q12802	A-kinase anchor protein 13	DEG_SCF_TRCP1_1	390:395	DSGTVS	BTRC	0.9959	More...
Q9NUP1	Biogenesis of lysosome-related organelles complex 1 subunit 4	DEG_SCF_TRCP1_1	29:34	DSGTVS	BTRC	0.6321	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons