DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
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Degron:
LPTPSPE
Uniprot ID:
P0CG30
Source protein:
Glutathione S-transferase theta-2B
Source gene:
GSTT2B
Class:
DEG_SCF_FBW7_2
Location:
225:231
E3 ligase:
FBXW7
DEGRON score:
0.9414
ASA_SCORE:
81.3714
COIL:
0.7371
CONS_SCORE:
0.4296
DSS_SCORE:
0.2996
HELIX:
0.255
FCONS_SCORE:
1.1697
RIG_SCORE:
0.7128
Degron related mutations and impact score
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Degron
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Drug responses associated with GSTT2B mutations
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All proteins holding degron of LPTPSPE
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P0CG30
Glutathione S-transferase theta-2B
DEG_SCF_FBW7_2
225:231
LPTPSPE
FBXW7
0.9414
More...
Q13635
Protein patched homolog 1
DEG_SCF_FBW7_2
1193:1199
LPTPSPE
FBXW7
0.5527
More...
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