DegronMD

Uniprot ID: Q9BVV8

Source protein: Protein FAM174C

Source gene: FAM174C

Class: DEG_APCC_TPR_1

Location: 130:132

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.9695

ASA_SCORE: 144.3333

COIL: 0.9383

CONS_SCORE: 0.6737

DSS_SCORE: 0.8857

HELIX: 0.067

FCONS_SCORE: 0.9856

RIG_SCORE: 0.7295

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.E122K	SIDM00929	Chondrosarcoma	GDSC	NLR	DEG_APCC_TPR_1	0.1111

DegronMD: protein-targeted degradation, mutation and drug response to degrons