DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
PSTPYHS
Uniprot ID:
Q96PQ5
Source protein:
Putative protein phosphatase inhibitor 2-like protein 1
Source gene:
PPP1R2P1
Class:
DEG_SCF_FBW7_1
Location:
71:77
E3 ligase:
FBXW7
DEGRON score:
0.9865
ASA_SCORE:
65.1714
COIL:
0.8599
CONS_SCORE:
0.7373
DSS_SCORE:
0.5659
HELIX:
0.0747
FCONS_SCORE:
1.0949
RIG_SCORE:
0.6534
Degron related mutations and impact score
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Drug responses associated with PPP1R2P1 mutations
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All proteins holding degron of PSTPYHS
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
P41236
Protein phosphatase inhibitor 2
DEG_SCF_FBW7_1
71:77
PSTPYHS
FBXW7
0.9989
More...
Q96PQ5
Putative protein phosphatase inhibitor 2-like protein 1
DEG_SCF_FBW7_1
71:77
PSTPYHS
FBXW7
0.9865
More...
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