DegronMD: protein-targeted degradation, mutation and drug response to degrons
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Degron:
PTPGPT
Uniprot ID:
I3L273
Source protein:
Golgi-associated olfactory signaling regulator
Source gene:
GFY
Class:
DEG_SCF_FBW7_1
Location:
137:142
E3 ligase:
FBXW7
DEGRON score:
0.9799
ASA_SCORE:
80.5
COIL:
0.9713
CONS_SCORE:
0
DSS_SCORE:
0.8725
HELIX:
0.0103
FCONS_SCORE:
0
RIG_SCORE:
0.4482
Degron related mutations and impact score
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Drug responses associated with GFY mutations
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All proteins holding degron of PTPGPT
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
I3L273
Golgi-associated olfactory signaling regulator
DEG_SCF_FBW7_1
137:142
PTPGPT
FBXW7
0.9799
More...
Q86XN7
Proline and serine-rich protein 1
DEG_SCF_FBW7_1
380:385
PTPGPT
FBXW7
0.9916
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