DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
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Degron:
VFTST
Uniprot ID:
Q9H195
Source protein:
Mucin-3B
Source gene:
MUC3B
Class:
DEG_SPOP_SBC_1
Location:
774:778
E3 ligase:
SPOP
DEGRON score:
0.752
ASA_SCORE:
96.6
COIL:
0.9098
CONS_SCORE:
0.5794
DSS_SCORE:
0.5216
HELIX:
0.0178
FCONS_SCORE:
1.0402
RIG_SCORE:
0.7984
Degron related mutations and impact score
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Degron
Degron class
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Drug responses associated with MUC3B mutations
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All proteins holding degron of VFTST
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
Q02505
Mucin-3A
DEG_SPOP_SBC_1
2860:2864
VFTST
SPOP
0.9693
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Q9H195
Mucin-3B
DEG_SPOP_SBC_1
774:778
VFTST
SPOP
0.752
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