DegronMD

Uniprot ID: Q9NYB0

Source protein: Telomeric repeat-binding factor 2-interacting protein 1

Source gene: TERF2IP

Class: DEG_APCC_KENBOX_2

Location: 148:152

E3 ligase: APC,CDC20,FZR1

DEGRON score: 0.6866

ASA_SCORE: 58.88

COIL: 0.303

CONS_SCORE: 0.5349

DSS_SCORE: 0.3465

HELIX: 0.6914

FCONS_SCORE: 0.8149

RIG_SCORE: 0.8017

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.G160C	DO229024	LICA	ICGC	VKENA	DEG_APCC_KENBOX_2	0.1111

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
A6H8Y1	Transcription factor TFIIIB component B'' homolog	DEG_APCC_KENBOX_2	2076:2080	VKENA	APC,CDC20,FZR1	0.9632	More...
Q9NYB0	Telomeric repeat-binding factor 2-interacting protein 1	DEG_APCC_KENBOX_2	148:152	VKENA	APC,CDC20,FZR1	0.6866	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons