DegronMD

Uniprot ID: A8MTL3

Source protein: RING finger protein 212B

Source gene: RNF212B

Class: DEG_SCF_FBW7_1

Location: 161:166

E3 ligase: FBXW7

DEGRON score: 0.9805

ASA_SCORE: 101.9333

COIL: 0.9585

CONS_SCORE: 0.4628

DSS_SCORE: 0.6411

HELIX: 0.033

FCONS_SCORE: 1.0388

RIG_SCORE: 0.6162

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.S171R	SIDM00997	Thyroid Gland Carcinoma	GDSC	VTPRPS	DEG_SCF_FBW7_1	0.1944

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
P55001	Microfibrillar-associated protein 2	DEG_SCF_FBW7_1	53:58	VTPRPS	FBXW7	0.9226	More...
A8MTL3	RING finger protein 212B	DEG_SCF_FBW7_1	161:166	VTPRPS	FBXW7	0.9805	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons