DegronMD - H7BZ55(CROCC2)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.S622Y	SIDM01184	Bladder Carcinoma	GDSC	QRDSLAAMA	DEG_APCC_DBOX_1	619:627	Mutation altering degron motif	0.6009
p.A184T	SIDM00845	Burkitt's Lymphoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.2778
p.R51W	SIDM00600	Thyroid Gland Carcinoma	GDSC	PTPVPT	DEG_SCF_FBW7_1	55:60	Mutation rewiring degron network	0.2222
p.G166S	SIDM00919	Ovarian Carcinoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00203	Ewing's Sarcoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00254	Neuroblastoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00672	Hepatocellular Carcinoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00116	Non-Small Cell Lung Carcinoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00926	Non-Small Cell Lung Carcinoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00261	Ewing's Sarcoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111
p.G166S	SIDM00628	Breast Carcinoma	GDSC	LREQLEHMK	DEG_APCC_DBOX_1	174:182	Mutation rewiring degron network	0.1111

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons