DegronMD

Uniprot ID: H7BZ55

Source protein: Ciliary rootlet coiled-coil protein 2

Source gene: CROCC2

Class: DEG_SCF_FBW7_1

Location: 55:60

E3 ligase: FBXW7

DEGRON score: 0.96

ASA_SCORE: 81.9833

COIL: 0.8433

CONS_SCORE: 0.2502

DSS_SCORE: 0.6253

HELIX: 0.1375

FCONS_SCORE: 0.6182

RIG_SCORE: 0.6701

Mutation	Sample	Cancer	Dataset	Degron	Degron class	Impact score
p.R51W	SIDM00600	Thyroid Gland Carcinoma	GDSC	PTPVPT	DEG_SCF_FBW7_1	0.2222

Uniprot ID	Source protein	Degron class	Location	Hit	E3 ligase	Degron score	Detail
O15078	Centrosomal protein of 290 kDa	DEG_SCF_FBW7_1	1611:1616	PTPVPT	FBXW7	0.9178	More...
P59797	Selenoprotein V	DEG_SCF_FBW7_1	106:111	PTPVPT	FBXW7	0.9907	More...
H7BZ55	Ciliary rootlet coiled-coil protein 2	DEG_SCF_FBW7_1	55:60	PTPVPT	FBXW7	0.96	More...

DegronMD: protein-targeted degradation, mutation and drug response to degrons