DegronMD: protein-targeted degradation, mutation and drug response to degrons
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BSML
CPH
CGC
Degron:
PTPVPT
Uniprot ID:
P59797
Source protein:
Selenoprotein V
Source gene:
SELENOV
Class:
DEG_SCF_FBW7_1
Location:
106:111
E3 ligase:
FBXW7
DEGRON score:
0.9907
ASA_SCORE:
97.4333
COIL:
0.9775
CONS_SCORE:
0.6213
DSS_SCORE:
0.5233
HELIX:
0.007
FCONS_SCORE:
1.15
RIG_SCORE:
0.6374
Degron related mutations and impact score
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Drug responses associated with SELENOV mutations
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All proteins holding degron of PTPVPT
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Uniprot ID
Source protein
Degron class
Location
Hit
E3 ligase
Degron score
Detail
O15078
Centrosomal protein of 290 kDa
DEG_SCF_FBW7_1
1611:1616
PTPVPT
FBXW7
0.9178
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H7BZ55
Ciliary rootlet coiled-coil protein 2
DEG_SCF_FBW7_1
55:60
PTPVPT
FBXW7
0.96
More...
P59797
Selenoprotein V
DEG_SCF_FBW7_1
106:111
PTPVPT
FBXW7
0.9907
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