DegronMD - O76041(NEBL)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D8Y	TCGA-55-A490	LUAD	TCGA	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.7325
p.D8Y	TCGA-55-A490	LUAD	TCGA	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.7325
p.D8Y	DO229060	LICA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.7325
p.D8Y	DO229060	LICA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.7325
p.D8Y	DO24596	LUAD	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.7325
p.D8Y	DO24596	LUAD	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.7325
p.K740Q	TCGA-A5-A0G2	UCEC	TCGA	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation substituting flanking lysine	0.3333
p.K740Q	DO41235	UCEC	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation substituting flanking lysine	0.3333
p.I18M	TCGA-AN-A0AM	BRCA	TCGA	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.0556
p.I18M	TCGA-AN-A0AM	BRCA	TCGA	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.0556
p.I18M	DO4191	BRCA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.0556
p.I18M	DO4191	BRCA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.0556
p.R720I	TCGA-AP-A0LM	UCEC	TCGA	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0833
p.R720I	DO43306	UCEC	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0833
p.D11Y	TCGA-BS-A0UF	UCEC	TCGA	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.25
p.D11Y	TCGA-BS-A0UF	UCEC	TCGA	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.25
p.D11Y	DO8264	COAD	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.25
p.D11Y	DO8264	COAD	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.25
p.D11Y	DO41488	UCEC	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.25
p.D11Y	DO41488	UCEC	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.25
p.E14K	TCGA-C8-A1HM	BRCA	TCGA	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1667
p.E14K	TCGA-C8-A1HM	BRCA	TCGA	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1667
p.E14K	DO3904	BRCA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1667
p.E14K	DO3904	BRCA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1667
p.S730R	TCGA-CG-4466	STAD	TCGA	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.6316
p.S730R	DO38695	STAD	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.6316
p.S730R	SIDM00404	B-Cell Non-Hodgkin's Lymphoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.6316
p.S730R	ACH-002307	Lymphoma	CCLE	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.6316
p.S730R	SU-DHL-16	haematopoietic and lymphoid tissue	COSMIC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.6316
p.A726T	TCGA-D9-A6EC	SKCM	TCGA	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.25
p.A726T	DO50291	SKCM	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.25
p.E14G	TCGA-EO-A22X	UCEC	TCGA	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1667
p.E14G	TCGA-EO-A22X	UCEC	TCGA	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1667
p.E14G	DO43907	UCEC	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1667
p.E14G	DO43907	UCEC	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1667
p.L723M	TCGA-FD-A6TH	BLCA	TCGA	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.1667
p.L723M	DO49763	BLCA	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.1667
p.E15K	TCGA-FW-A3R5	SKCM	TCGA	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1389
p.E15K	TCGA-FW-A3R5	SKCM	TCGA	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1389
p.E15K	DO37406	SKCM	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1389
p.E15K	DO37406	SKCM	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1389
p.E743K	TCGA-WE-A8K1	SKCM	TCGA	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.1389
p.E743K	DO51280	SKCM	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.1389
p.A6S	DO225004	BRCA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.7588
p.A6S	DO225004	BRCA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.7588
p.S730N	DO229363	BTCA	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.5958
p.E16K	DO230326	COCA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1111
p.E16K	DO230326	COCA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1111
p.M735I	DO234412	ESAD	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.6507
p.Q4K	DO229027	LICA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6944
p.Q4K	DO229027	LICA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6944
p.V731L	DO45151	LIRI	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.5654
p.T728A	DO52365	LUSC	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01034	B-Lymphoblastic Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00435	Acute Myeloid Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00586	Hepatocellular Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00557	Neuroblastoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00588	Oral Cavity Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01004	Chronic Myelogenous Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00215	Colorectal Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00232	Kidney Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00572	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00584	Osteosarcoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00547	Non-Small Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00602	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00544	Neuroblastoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00548	Squamous Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00890	Melanoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00592	Oral Cavity Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00598	Squamous Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00354	Squamous Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00492	Glioblastoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00351	Oral Cavity Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00384	B-Cell Non-Hodgkin's Lymphoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01045	Endometrial Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00237	Non-Small Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01146	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01024	Esophageal Squamous Cell Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00298	Squamous Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00907	Burkitt's Lymphoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00576	Acute Myeloid Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00280	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00023	Esophageal Squamous Cell Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00469	Pancreatic Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00368	Small Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00560	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00494	Non-Small Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00363	Acute Myeloid Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00850	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00316	Glioblastoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00302	Other Solid Cancers	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01018	Hodgkin's Lymphoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01695	Acute Myeloid Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01659	Kidney Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01377	Ovarian Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01779	Gastric Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01347	Ovarian Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00161	Biliary Tract Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00163	Biliary Tract Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01435	Hepatocellular Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01575	Plasma Cell Myeloma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01446	Glioblastoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01690	Plasma Cell Myeloma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM00959	Acute Myeloid Leukemia	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01764	Non-Small Cell Lung Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.T728A	SIDM01391	Neuroblastoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.3056
p.F4L	DO26469	LUSC	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6981
p.F4L	DO26469	LUSC	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6981
p.E12K	DO222546	MELA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.2222
p.E12K	DO222546	MELA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.2222
p.E12K	DO222653	MELA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.2222
p.E12K	DO222653	MELA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.2222
p.P733L	DO222868	MELA	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation altering degron motif	0.7582
p.S746R	DO46372	OV	ICGC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0556
p.E12D	DO46368	OV	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.2222
p.E12D	DO46368	OV	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.2222
p.V18I	DO218861	SKCA	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.0556
p.V18I	DO218861	SKCA	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.0556
p.K10N	DO41758	UCEC	ICGC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.2778
p.K10N	DO41758	UCEC	ICGC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.2778
p.P4L	SIDM00454	Rhabdomyosarcoma	GDSC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6471
p.P4L	SIDM00454	Rhabdomyosarcoma	GDSC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6471
p.P4L	SIDM00633	Breast Carcinoma	GDSC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6471
p.P4L	SIDM00633	Breast Carcinoma	GDSC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6471
p.P4L	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6471
p.P4L	SIDM01677	Non-Small Cell Lung Carcinoma	GDSC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6471
p.D8N	SIDM00003	Melanoma	GDSC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6932
p.D8N	SIDM00003	Melanoma	GDSC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6932
p.D8N	SIDM00312	Plasma Cell Myeloma	GDSC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6932
p.D8N	SIDM00312	Plasma Cell Myeloma	GDSC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6932
p.D8N	ACH-000183	Myeloma	CCLE	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6932
p.D8N	ACH-000183	Myeloma	CCLE	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6932
p.D8N	ACH-002159	Skin Cancer	CCLE	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6932
p.D8N	ACH-002159	Skin Cancer	CCLE	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6932
p.D8N	L-363	haematopoietic and lymphoid tissue	COSMIC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6932
p.D8N	L-363	haematopoietic and lymphoid tissue	COSMIC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6932
p.D8N	M14	skin	COSMIC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6932
p.D8N	M14	skin	COSMIC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6932
p.V5A	SIDM00254	Neuroblastoma	GDSC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6936
p.V5A	SIDM00254	Neuroblastoma	GDSC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6936
p.V5A	ACH-002283	Neuroblastoma	CCLE	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6936
p.V5A	ACH-002283	Neuroblastoma	CCLE	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6936
p.V5A	NB5	autonomic ganglia	COSMIC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.6936
p.V5A	NB5	autonomic ganglia	COSMIC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.6936
p.R720K	SIDM01042	Breast Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0833
p.S746T	SIDM01138	Pancreatic Carcinoma	GDSC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0556
p.S746T	ACH-000139	Pancreatic Cancer	CCLE	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0556
p.S746T	PANC-03-27	pancreas	COSMIC	LSVTPEME	DEG_SCF_FBW7_2	729:736	Mutation rewiring degron network	0.0556
p.C5R	ACH-000971	Colon/Colorectal Cancer	CCLE	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.8301
p.C5R	ACH-000971	Colon/Colorectal Cancer	CCLE	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.8301
p.C5R	HCT-116	large intestine	COSMIC	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation altering degron motif	0.8301
p.C5R	HCT-116	large intestine	COSMIC	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation altering degron motif	0.8301
p.P14S	ACH-001119	Lymphoma	CCLE	VPVFED	LIG_APCC_ABBA_1	3:8	Mutation rewiring degron network	0.1667
p.P14S	ACH-001119	Lymphoma	CCLE	RVPVFED	LIG_APCC_ABBAyCdc20_2	2:8	Mutation rewiring degron network	0.1667

DegronMD: protein-targeted degradation, mutation and drug response to degrons

NEBL

UniProt ID: O76041

Entrez ID: 10529

Protein name: Nebulette (Actin-binding Z-disk protein)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for NEBL in