DegronMD - O95153(TSPOAP1)

TSPOAP1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P1214T	SIDM01307	Colorectal Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	1200:1204	Mutation rewiring degron network	0.0556
p.T1850R	SIDM01210	Glioblastoma	GDSC	PRTPQAE	DEG_SCF_FBW7_2	1840:1846	Mutation rewiring degron network	0.2222
p.T1850R	KNS-81-FD	central nervous system	COSMIC	PRTPQAE	DEG_SCF_FBW7_2	1840:1846	Mutation rewiring degron network	0.2222
p.V1055L	SIDM01617	Endometrial Carcinoma	GDSC	MSPHGE	LIG_APCC_ABBA_1	1060:1065	Mutation rewiring degron network	0.1944
p.G1466R	SIDM01619	Endometrial Carcinoma	GDSC	ERGGLPVIE	DEG_APCC_DBOX_1	1448:1456	Mutation rewiring degron network	0.0556
p.I1439N	GP5d	large intestine	COSMIC	ERGGLPVIE	DEG_APCC_DBOX_1	1448:1456	Mutation rewiring degron network	0.0833
p.P1071T	U-87-MG	central nervous system	COSMIC	MSPHGE	LIG_APCC_ABBA_1	1060:1065	Mutation rewiring degron network	0.1667
p.P1170T	OCI-LY7	haematopoietic and lymphoid tissue	COSMIC	ASTST	DEG_SPOP_SBC_1	1169:1173	Mutation altering degron motif	0.7031
p.P1059T	SNU-C5	large intestine	COSMIC	MSPHGE	LIG_APCC_ABBA_1	1060:1065	Mutation rewiring degron network	0.3056
p.G1161E	NCI-H2023	lung	COSMIC	ASTST	DEG_SPOP_SBC_1	1169:1173	Mutation rewiring degron network	0.1111
p.S1195L	LS-411N	large intestine	COSMIC	PASSS	DEG_SPOP_SBC_1	1200:1204	Mutation rewiring degron network	0.1944

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*NOTE: the Kaplan plots were collected from OncoLnc