p.R310C | TCGA-14-0867 | GBM | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation altering degron motif | 0.8301 |
p.R310C | DO11675 | GBM | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation altering degron motif | 0.8301 |
p.K304N | TCGA-22-5481 | LUSC | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation substituting flanking lysine | 0.2778 |
p.K304N | DO27160 | LUSC | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation substituting flanking lysine | 0.2778 |
p.R162W | TCGA-2W-A8YY | CESC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation altering degron motif | 0.7523 |
p.R162W | DO223732 | CESC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation altering degron motif | 0.7523 |
p.S155A | TCGA-39-5022 | LUSC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.S155A | DO27604 | LUSC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.D166Y | TCGA-56-8504 | LUSC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.D166Y | DO45437 | LUSC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.I196M | TCGA-56-8622 | LUSC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.25 |
p.I196M | DO45449 | LUSC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.25 |
p.Q164H | TCGA-56-8629 | LUSC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.3056 |
p.Q164H | DO45451 | LUSC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.3056 |
p.R203T | TCGA-56-A49D | LUSC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.0556 |
p.R203T | DO45475 | LUSC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.0556 |
p.A188S | TCGA-79-5596 | LUSC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.7588 |
p.A188S | DO27357 | LUSC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.7588 |
p.R300W | TCGA-91-7771 | LUAD | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.0556 |
p.R300W | DO25807 | LUAD | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.0556 |
p.P192L | TCGA-AX-A2HD | UCEC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.7582 |
p.P192L | DO42608 | UCEC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.7582 |
p.R198Q | TCGA-B0-5098 | KIRC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1944 |
p.R198Q | DO18938 | KIRC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1944 |
p.K185E | TCGA-B5-A3FC | UCEC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.591 |
p.K185E | DO41871 | UCEC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.591 |
p.R309L | TCGA-BA-A6DA | HNSC | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.3056 |
p.R309L | DO44448 | HNSC | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.3056 |
p.D319N | TCGA-BS-A0UF | UCEC | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | TCGA-E6-A1LX | UCEC | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | DO41020 | UCEC | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | DO41488 | UCEC | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | SIDM00583 | Pancreatic Carcinoma | GDSC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | ACH-000164 | Pancreatic Cancer | CCLE | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | ACH-001107 | Pancreatic Cancer | CCLE | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.D319N | KP-1N | pancreas | COSMIC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.25 |
p.R309Q | TCGA-CM-4743 | COAD | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.3056 |
p.R309Q | DO8103 | COAD | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.3056 |
p.R310H | TCGA-D1-A103 | UCEC | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation altering degron motif | 0.8244 |
p.R310H | DO42312 | UCEC | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation altering degron motif | 0.8244 |
p.V315A | TCGA-DF-A2KU | UCEC | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation altering degron motif | 0.5825 |
p.V315A | DO223286 | UCEC | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation altering degron motif | 0.5825 |
p.G168D | TCGA-DI-A1BU | UCEC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1944 |
p.G168D | DO42023 | UCEC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1944 |
p.W322L | TCGA-EE-A3AC | SKCM | TCGA | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.1667 |
p.W322L | DO37631 | SKCM | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.1667 |
p.I180V | TCGA-EO-A22R | UCEC | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1944 |
p.I180V | DO42713 | UCEC | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1944 |
p.R159Q | TCGA-EO-A22T | UCEC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation altering degron motif | 0.6218 |
p.R159Q | DO42320 | UCEC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation altering degron motif | 0.6218 |
p.S155Y | TCGA-GN-A265 | SKCM | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.S155Y | DO37491 | SKCM | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.E151K | TCGA-GN-A4U4 | SKCM | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1389 |
p.E151K | DO51256 | SKCM | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1389 |
p.V190A | TCGA-IB-7651 | PAAD | TCGA | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.6936 |
p.V190A | DO46657 | PAAD | ICGC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.6936 |
p.S155C | TCGA-IR-A3LL | CESC | TCGA | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.S155C | DO44362 | CESC | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.25 |
p.V152A | DO228483 | BRCA | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1667 |
p.V152A | DO230334 | COCA | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1667 |
p.V152A | DO229013 | COCA | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1667 |
p.V152A | DO229003 | COCA | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1667 |
p.V152A | DO229505 | LAML | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1667 |
p.V152A | DO228947 | LICA | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1667 |
p.N323D | DO224756 | LAML | ICGC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.1389 |
p.I153T | DO229211 | THCA | ICGC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.1944 |
p.E149Q | SIDM01048 | Plasma Cell Myeloma | GDSC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.0833 |
p.E149Q | ACH-000821 | Myeloma | CCLE | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.0833 |
p.E149Q | EJM | haematopoietic and lymphoid tissue | COSMIC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.0833 |
p.L199P | SIDM01004 | Chronic Myelogenous Leukemia | GDSC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1667 |
p.L199P | SIDM00250 | Esophageal Squamous Cell Carcinoma | GDSC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1667 |
p.L199P | ACH-000917 | Esophageal Cancer | CCLE | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1667 |
p.L199P | ACH-000983 | Leukemia | CCLE | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1667 |
p.L199P | TE-4 | oesophagus | COSMIC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1667 |
p.L199P | KCL-22 | haematopoietic and lymphoid tissue | COSMIC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.1667 |
p.V190M | SIDM00845 | Burkitt's Lymphoma | GDSC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.7208 |
p.V190M | ACH-000992 | Head and Neck Cancer | CCLE | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation altering degron motif | 0.7208 |
p.E172K | SIDM00411 | Pancreatic Carcinoma | GDSC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.0833 |
p.E172K | ACH-000332 | Pancreatic Cancer | CCLE | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.0833 |
p.E172K | YAPC | pancreas | COSMIC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.0833 |
p.S154F | SIDM00142 | Endometrial Carcinoma | GDSC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.2222 |
p.S154F | ACH-000864 | Endometrial/Uterine Cancer | CCLE | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.2222 |
p.S154F | ACH-001283 | Bone Cancer | CCLE | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.2222 |
p.S154F | COLO-684 | endometrium | COSMIC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.2222 |
p.E182D | SIDM00965 | Small Cell Lung Carcinoma | GDSC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.25 |
p.E182D | ACH-000800 | Lung Cancer | CCLE | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.25 |
p.E182D | NCI-H446 | lung | COSMIC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.25 |
p.T202M | SIDM00936 | Bladder Carcinoma | GDSC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.0833 |
p.T202M | ACH-000142 | Bladder Cancer | CCLE | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.0833 |
p.T202M | CAL-29 | urinary tract | COSMIC | KPPAEVVPG | DEG_SIAH_1 | 185:193 | Mutation rewiring degron network | 0.0833 |
p.S318N | SIDM00721 | Small Cell Lung Carcinoma | GDSC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.2778 |
p.S318N | ACH-002171 | Lung Cancer | CCLE | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.2778 |
p.S318N | NCI-H250 | lung | COSMIC | RHSLYVD | LIG_APCC_ABBAyCdc20_2 | 310:316 | Mutation rewiring degron network | 0.2778 |
p.R162Q | SIDM01445 | Gastric Carcinoma | GDSC | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation altering degron motif | 0.6218 |
p.V165L | ACH-000435 | Endometrial/Uterine Cancer | CCLE | LRLFRE | LIG_APCC_ABBA_1 | 158:163 | Mutation rewiring degron network | 0.2778 |