DegronMD - P23515(OMG)

FUNCTION: Cell adhesion molecule contributing to the interactive process required for myelination in the central nervous system.

GO - Biological processes (BP): cell adhesion [GO:0007155]; neuron projection regeneration [GO:0031102]

GO - Molecular function (MF):

GO - Cellular component (CC): anchored component of membrane [GO:0031225]; plasma membrane [GO:0005886]

Choose a PDB ID:
Open in full screen with detailed sequence annotations

Data table is loading....

Show entries

Search:

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.P253L	TCGA-61-2009	OV	TCGA	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation altering degron motif	0.7582
p.P253L	DO28992	OV	ICGC	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation altering degron motif	0.7582
p.S417Y	TCGA-AX-A2HC	UCEC	TCGA	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation altering degron motif	0.712
p.S417Y	DO41572	UCEC	ICGC	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation altering degron motif	0.712
p.G251W	SIDM00958	Chronic Myelogenous Leukemia	GDSC	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation altering degron motif	0.6714
p.G251W	ACH-000920	Leukemia	CCLE	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation altering degron motif	0.6714
p.G251W	CML-T1	haematopoietic and lymphoid tissue	COSMIC	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation altering degron motif	0.6714
p.K412N	TCGA-AA-3984	COAD	TCGA	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation altering degron motif	0.5806
p.K412N	DO9002	COAD	ICGC	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation altering degron motif	0.5806
p.A330T	TCGA-EB-A3Y7	SKCM	TCGA	FVPYPE	LIG_APCC_ABBA_1	331:336	Mutation rewiring degron network	0.3056
p.A330T	DO37499	SKCM	ICGC	FVPYPE	LIG_APCC_ABBA_1	331:336	Mutation rewiring degron network	0.3056
p.K262Q	TCGA-AJ-A5DW	UCEC	TCGA	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation substituting flanking lysine	0.2778
p.K262Q	DO50075	UCEC	ICGC	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation substituting flanking lysine	0.2778
p.T409K	DO229019	LICA	ICGC	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation rewiring degron network	0.2778
p.A419E	DO229031	LICA	ICGC	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation rewiring degron network	0.2778
p.A247V	SIDM01103	Squamous Cell Lung Carcinoma	GDSC	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation rewiring degron network	0.2778
p.A247V	ACH-000665	Lung Cancer	CCLE	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation rewiring degron network	0.2778
p.A247V	SK-MES-1	lung	COSMIC	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation rewiring degron network	0.2778
p.A421V	ACH-001379	Pancreatic Cancer	CCLE	VKTPLPS	DEG_SCF_FBW7_1	411:417	Mutation rewiring degron network	0.2222
p.E244A	TCGA-06-1802	GBM	TCGA	VIGTPCST	DEG_SCF_FBW7_1	249:256	Mutation rewiring degron network	0.1944

Showing 1 to 20 of 35 entries

Previous1 2Next

Kaplan plot for OMG in

Select cancer type:
Download patient class data (Lower:Upper = 50%:50%)

*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

OMG

UniProt ID: P23515

Entrez ID: 4974

Protein name: Oligodendrocyte-myelin glycoprotein

External links: UniprotKB HGNC RefSeq COSMIC

Data table is loading....

Kaplan plot for OMG in