p.T146S | TCGA-06-0145 | GBM | TCGA | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.7116 |
p.T146S | DO13192 | GBM | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.7116 |
p.E163D | TCGA-37-5819 | LUSC | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.E163D | DO26479 | LUSC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.A161V | TCGA-39-5034 | LUSC | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.0556 |
p.A161V | DO26854 | LUSC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.0556 |
p.H143Q | TCGA-44-3398 | LUAD | TCGA | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.7582 |
p.H143Q | DO25030 | LUAD | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.7582 |
p.M162T | TCGA-44-5644 | LUAD | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.0833 |
p.M162T | DO25153 | LUAD | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.0833 |
p.A172V | TCGA-A5-A0G2 | UCEC | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.5825 |
p.A172V | DO41235 | UCEC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.5825 |
p.E163K | TCGA-CN-A63Y | HNSC | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.E163K | DO44422 | HNSC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.L167S | TCGA-D8-A147 | BRCA | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.2222 |
p.L167S | DO4347 | BRCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.2222 |
p.T141N | TCGA-EB-A85J | SKCM | TCGA | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.5944 |
p.T141N | DO50297 | SKCM | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.5944 |
p.D170N | TCGA-EE-A2MR | SKCM | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.D170N | DO225232 | BRCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.D170N | DO37819 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.A176T | TCGA-F4-6460 | COAD | TCGA | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.6028 |
p.A176T | DO8850 | COAD | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.6028 |
p.P158L | TCGA-FR-A3YN | SKCM | TCGA | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1111 |
p.P158L | DO38111 | SKCM | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1111 |
p.G136E | TCGA-FS-A1ZW | SKCM | TCGA | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1111 |
p.G136E | TCGA-FS-A1ZW | SKCM | TCGA | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.2222 |
p.G136E | DO37519 | SKCM | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1111 |
p.G136E | DO37519 | SKCM | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.2222 |
p.S152F | TCGA-OD-A75X | SKCM | TCGA | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.2778 |
p.S152F | TCGA-OD-A75X | SKCM | TCGA | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1389 |
p.S152F | DO229459 | SKCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.2778 |
p.S152F | DO229459 | SKCA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1389 |
p.S152F | DO229462 | SKCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.2778 |
p.S152F | DO229462 | SKCA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1389 |
p.S152F | DO48601 | SKCM | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.2778 |
p.S152F | DO48601 | SKCM | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1389 |
p.K174N | DO51951 | BLCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.6918 |
p.E160Q | DO3221 | BRCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.0556 |
p.G184C | DO223732 | CESC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1389 |
p.K145Q | DO8264 | COAD | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6944 |
p.K145Q | DO8264 | COAD | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.6944 |
p.K174E | DO229010 | COCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7022 |
p.K174E | DO229013 | COCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7022 |
p.K174E | DO229016 | COCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7022 |
p.K174E | DO229003 | COCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7022 |
p.K174E | DO229005 | COCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7022 |
p.S147P | DO229010 | COCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.S147P | DO229013 | COCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.S147P | DO229016 | COCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.S147P | DO229003 | COCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.S147P | DO229005 | COCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.S147P | DO234205 | ESAD | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.S147P | DO234285 | ESAD | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6752 |
p.G184V | DO234468 | ESAD | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1389 |
p.V134I | DO233650 | GACA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.0556 |
p.V134I | DO233650 | GACA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1667 |
p.E170K | DO15799 | HNSC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.E170K | DO44422 | HNSC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.E170K | DO37635 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.E170K | DO37631 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.E170K | DO47282 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.E170K | DO47268 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.E170K | DO37778 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.3056 |
p.H143Y | DO228950 | LICA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.6118 |
p.H143Y | DO229061 | LICA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.6118 |
p.T139N | DO228971 | LICA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1944 |
p.T139N | DO228971 | LICA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.3056 |
p.W180C | DO229050 | LICA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.25 |
p.H137Y | DO229052 | LICA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1389 |
p.H137Y | DO229052 | LICA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.25 |
p.T173N | DO229006 | LICA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7055 |
p.N183S | DO23651 | LUAD | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1667 |
p.T168S | DO230529 | LUSC | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.25 |
p.T168S | SIDM00570 | Gastric Carcinoma | GDSC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.25 |
p.T168S | SIDM00591 | Oral Cavity Carcinoma | GDSC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.25 |
p.T168S | SIDM01618 | B-Lymphoblastic Leukemia | GDSC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.25 |
p.R159S | DO224563 | LUSC | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.0833 |
p.G133E | DO220873 | MELA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1389 |
p.M162I | DO220889 | MELA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.0833 |
p.L144P | DO220906 | MELA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.6471 |
p.L144P | DO220906 | MELA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation altering degron motif | 0.6471 |
p.G184S | DO222658 | MELA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1389 |
p.G184S | DO37599 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1389 |
p.L156V | DO222678 | MELA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1667 |
p.L156V | DO37770 | SKCM | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1667 |
p.N155D | DO232445 | PBCA | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1944 |
p.N155D | DO232445 | PBCA | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.0556 |
p.C169W | DO48626 | SKCM | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.2778 |
p.T173I | DO229227 | THCA | ICGC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7078 |
p.I153T | DO42312 | UCEC | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.25 |
p.I153T | DO42312 | UCEC | ICGC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1111 |
p.E160D | DO41020 | UCEC | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.0556 |
p.S147F | DO43755 | UCEC | ICGC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation altering degron motif | 0.7982 |
p.S153R | SIDM00135 | Breast Carcinoma | GDSC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.25 |
p.S153R | SIDM00135 | Breast Carcinoma | GDSC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1111 |
p.S153R | ACH-000148 | Breast Cancer | CCLE | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.25 |
p.S153R | ACH-000148 | Breast Cancer | CCLE | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1111 |
p.S153R | ACH-000532 | Colon/Colorectal Cancer | CCLE | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.25 |
p.S153R | ACH-000532 | Colon/Colorectal Cancer | CCLE | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1111 |
p.S153R | Hs-578-T | breast | COSMIC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.25 |
p.S153R | Hs-578-T | breast | COSMIC | FTLHLE | LIG_APCC_ABBA_1 | 140:145 | Mutation rewiring degron network | 0.1111 |
p.S177R | SIDM00703 | Non-Small Cell Lung Carcinoma | GDSC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7427 |
p.Q185H | SIDM00882 | Breast Carcinoma | GDSC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.Q185H | ACH-000277 | Breast Cancer | CCLE | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.Q185H | HCC1419 | breast | COSMIC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation rewiring degron network | 0.1111 |
p.P171T | SIDM00160 | Biliary Tract Carcinoma | GDSC | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7031 |
p.P171T | ACH-000377 | Bile Duct Cancer | CCLE | PATPAAS | DEG_SCF_FBW7_1 | 171:177 | Mutation altering degron motif | 0.7031 |
p.P158S | SK-MES-1 | lung | COSMIC | LETPKPS | DEG_SCF_FBW7_1 | 144:150 | Mutation rewiring degron network | 0.1111 |