p.S172L | TCGA-21-1071 | LUSC | TCGA | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking phosphorylation signal | 0.7222 |
p.S172L | DO26918 | LUSC | ICGC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking phosphorylation signal | 0.7222 |
p.H866Y | TCGA-AJ-A3BG | UCEC | TCGA | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.6118 |
p.H866Y | DO42633 | UCEC | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.6118 |
p.D861H | TCGA-C8-A8HQ | BRCA | TCGA | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation rewiring degron network | 0.25 |
p.D861H | DO1071 | BRCA | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation rewiring degron network | 0.25 |
p.D861H | DO219623 | BRCA | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation rewiring degron network | 0.25 |
p.P867T | TCGA-CH-5762 | PRAD | TCGA | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.5919 |
p.P867T | DO36228 | PRAD | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.5919 |
p.Q876P | TCGA-D1-A103 | UCEC | TCGA | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation rewiring degron network | 0.2222 |
p.Q876P | DO42312 | UCEC | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation rewiring degron network | 0.2222 |
p.K171N | TCGA-D1-A17Q | UCEC | TCGA | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.75 |
p.K171N | DO41903 | UCEC | ICGC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.75 |
p.K157T | TCGA-EY-A1G8 | UCEC | TCGA | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.5278 |
p.K157T | DO43578 | UCEC | ICGC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.5278 |
p.K646N | TCGA-MV-A51V | BLCA | TCGA | ILVTPLKS | DEG_SCF_FBW7_1 | 650:657 | Mutation blocking ubiquitination signal | 0.6667 |
p.K646N | DO474 | BLCA | ICGC | ILVTPLKS | DEG_SCF_FBW7_1 | 650:657 | Mutation blocking ubiquitination signal | 0.6667 |
p.C870Y | TCGA-PJ-A5Z8 | KIRP | TCGA | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.5976 |
p.C870Y | DO44480 | KIRP | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.5976 |
p.A642D | DO228985 | LICA | ICGC | ILVTPLKS | DEG_SCF_FBW7_1 | 650:657 | Mutation rewiring degron network | 0.1111 |
p.A642D | DO229037 | LICA | ICGC | ILVTPLKS | DEG_SCF_FBW7_1 | 650:657 | Mutation rewiring degron network | 0.1111 |
p.T161N | DO229029 | LICA | ICGC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking phosphorylation signal | 0.6389 |
p.L158M | DO229047 | LICA | ICGC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.1111 |
p.L158M | DO229049 | LICA | ICGC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.1111 |
p.E882Q | DO23490 | LINC | ICGC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation rewiring degron network | 0.0556 |
p.L651I | DO222653 | MELA | ICGC | ILVTPLKS | DEG_SCF_FBW7_1 | 650:657 | Mutation altering degron motif | 0.6063 |
p.P654L | DO218900 | SKCA | ICGC | ILVTPLKS | DEG_SCF_FBW7_1 | 650:657 | Mutation altering degron motif | 0.7582 |
p.K167N | SIDM00683 | Prostate Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation altering degron motif | 0.6918 |
p.K167N | ACH-000977 | lymph node | CCLE | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation altering degron motif | 0.6918 |
p.K157N | SIDM01016 | T-Lymphoblastic Leukemia | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.5278 |
p.K157N | SIDM00120 | Prostate Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.5278 |
p.K157N | SIDM00500 | Colorectal Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation blocking ubiquitination signal | 0.5278 |
p.C164R | SIDM00672 | Hepatocellular Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.2778 |
p.C164R | SIDM00773 | Non-Cancerous | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.2778 |
p.C164R | SIDM00807 | Bladder Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.2778 |
p.C164R | SIDM00774 | Breast Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.2778 |
p.K156I | SIDM01171 | Glioblastoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation substituting flanking lysine | 0.1667 |
p.K156I | ACH-000571 | Brain Cancer | CCLE | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation substituting flanking lysine | 0.1667 |
p.K156I | T98G | central nervous system | COSMIC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation substituting flanking lysine | 0.1667 |
p.K156N | SIDM00323 | B-Cell Non-Hodgkin's Lymphoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation substituting flanking lysine | 0.1667 |
p.K156N | TK | haematopoietic and lymphoid tissue | COSMIC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation substituting flanking lysine | 0.1667 |
p.P867L | SIDM00238 | Ovarian Carcinoma | GDSC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.6471 |
p.P867L | ACH-000947 | Ovarian Cancer | CCLE | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.6471 |
p.P867L | OVK-18 | ovary | COSMIC | NRHPLECLP | DEG_APCC_DBOX_1 | 864:872 | Mutation altering degron motif | 0.6471 |
p.D176G | SIDM00699 | Small Cell Lung Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.1667 |
p.D176G | ACH-001138 | Lung Cancer | CCLE | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.1667 |
p.D176G | NCI-H2141 | lung | COSMIC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.1667 |
p.Q159R | SIDM01608 | Endometrial Carcinoma | GDSC | EKENN | DEG_APCC_KENBOX_2 | 166:170 | Mutation rewiring degron network | 0.1389 |