DegronMD - Q6P6B1(ERICH5)

ERICH5

UniProt ID: Q6P6B1

Entrez ID: 203111

Protein name: Glutamate-rich protein 5

External links: UniprotKB HGNC RefSeq COSMIC

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D51H	SIDM00745	Non-Small Cell Lung Carcinoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation rewiring degron network	0.1389
p.D51H	NCI-H1650	lung	COSMIC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation rewiring degron network	0.1389
p.D272H	SIDM00745	Non-Small Cell Lung Carcinoma	GDSC	PKENV	DEG_APCC_KENBOX_2	262:266	Mutation rewiring degron network	0.1667
p.D272H	NCI-H1650	lung	COSMIC	PKENV	DEG_APCC_KENBOX_2	262:266	Mutation rewiring degron network	0.1667
p.A215T	SIDM01011	B-Cell Non-Hodgkin's Lymphoma	GDSC	SKENE	DEG_APCC_KENBOX_2	222:226	Mutation rewiring degron network	0.1389
p.A215T	KARPAS-1106P	haematopoietic and lymphoid tissue	COSMIC	SKENE	DEG_APCC_KENBOX_2	222:226	Mutation rewiring degron network	0.1389
p.E226D	SIDM00143	Small Cell Lung Carcinoma	GDSC	SKENE	DEG_APCC_KENBOX_2	222:226	Mutation altering degron motif	0.5647
p.R59H	SIDM00875	Breast Carcinoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.R59H	SIDM01133	Other Solid Cancers	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.R59H	SIDM00412	B-Cell Non-Hodgkin's Lymphoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.R59H	SIDM00673	Breast Carcinoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.R59H	SIDM01173	Rhabdomyosarcoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.R59H	SIDM01710	Squamous Cell Lung Carcinoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.R59H	SIDM01752	Pancreatic Carcinoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation altering degron motif	0.8244
p.A215D	SIDM01072	Squamous Cell Lung Carcinoma	GDSC	SKENE	DEG_APCC_KENBOX_2	222:226	Mutation rewiring degron network	0.1389
p.A215D	HCC-15	lung	COSMIC	SKENE	DEG_APCC_KENBOX_2	222:226	Mutation rewiring degron network	0.1389
p.V54I	SIDM01617	Endometrial Carcinoma	GDSC	SRPPLQKLK	DEG_APCC_DBOX_1	58:66	Mutation rewiring degron network	0.2222

Kaplan plot for ERICH5 in

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*NOTE: the Kaplan plots were collected from OncoLnc