DegronMD - Q86SU0(ILDR1)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.D363N	TCGA-90-A4ED	LUSC	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.2222
p.D363N	ACH-001569	Skin Cancer	CCLE	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.2222
p.K525E	TCGA-AA-3811	COAD	TCGA	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation substituting flanking lysine	0.3333
p.P510S	TCGA-AP-A1DK	UCEC	TCGA	PPSY	ITCH	509:512	Mutation altering degron motif	0.6752
p.R433W	TCGA-BR-8081	STAD	TCGA	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433W	TCGA-BR-8081	STAD	TCGA	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433W	SIDM01265	Plasma Cell Myeloma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433W	SIDM01265	Plasma Cell Myeloma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R418M	TCGA-D3-A3CB	SKCM	TCGA	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.8632
p.P438L	TCGA-D3-A5GN	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0556
p.G367E	TCGA-DA-A3F8	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367E	TCGA-EE-A29D	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367E	TCGA-YG-AA3O	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367E	SIDM00545	Melanoma	GDSC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367E	ACH-000987	Skin Cancer	CCLE	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367E	Mewo	skin	COSMIC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.P358S	TCGA-EE-A2GL	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	TCGA-EE-A3J5	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	TCGA-FR-A726	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	TCGA-FR-A8YC	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	TCGA-GF-A6C9	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	TCGA-W3-AA1Q	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	SIDM01106	Melanoma	GDSC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	ACH-000822	Skin Cancer	CCLE	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.P358S	SK-MEL-24	skin	COSMIC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.5641
p.R365M	TCGA-EE-A2GT	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1667
p.P412L	TCGA-EE-A3AH	SKCM	TCGA	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1944
p.D423N	TCGA-GN-A4U4	SKCM	TCGA	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.5821
p.D423N	TCGA-Z2-A8RT	SKCM	TCGA	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.5821
p.P434L	TCGA-W3-A824	SKCM	TCGA	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.0833
p.P434L	TCGA-W3-A824	SKCM	TCGA	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1667
p.P434L	SIDM00164	Biliary Tract Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.0833
p.P434L	SIDM00164	Biliary Tract Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1667
p.E366Q	TCGA-YD-A9TA	SKCM	TCGA	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1389
p.P345L	DO222960	BTCA	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.0833
p.P345L	DO50668	ORCA	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.0833
p.P345L	DO51271	SKCM	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.0833
p.F350L	DO219732	CESC	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.2222
p.R407H	DO10068	COAD	ICGC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.0556
p.K436E	DO7962	COAD	ICGC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1111
p.R361M	DO7938	COAD	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.2778
p.V512A	DO227844	COCA	ICGC	PPSY	ITCH	509:512	Mutation altering degron motif	0.6936
p.S362N	DO48224	ESCA	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.25
p.D364G	DO44440	HNSC	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1944
p.G428W	DO20776	KIRP	ICGC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation altering degron motif	0.7825
p.R359H	DO50224	LGG	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation altering degron motif	0.8244
p.E422Q	DO228835	LICA	ICGC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.6744
p.S505R	DO229045	LICA	ICGC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation rewiring degron network	0.0833
p.S505R	DO229045	LICA	ICGC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.2222
p.R360K	DO220853	MELA	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.3056
p.G509R	DO220877	MELA	ICGC	PPSY	ITCH	509:512	Mutation altering degron motif	0.7568
p.G509R	DO48726	SKCM	ICGC	PPSY	ITCH	509:512	Mutation altering degron motif	0.7568
p.P415L	DO220902	MELA	ICGC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2778
p.P415L	DO220902	MELA	ICGC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0833
p.D504Y	DO36556	READ	ICGC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation rewiring degron network	0.0556
p.D504Y	DO36556	READ	ICGC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.1944
p.R510K	DO37659	SKCM	ICGC	PPSY	ITCH	509:512	Mutation altering degron motif	0.7237
p.E347K	DO37798	SKCM	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1389
p.R408K	DO37454	SKCM	ICGC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.0833
p.R426K	DO50284	SKCM	ICGC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation altering degron motif	0.7237
p.R421Q	DO48665	SKCM	ICGC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7329
p.R421Q	DO219787	UCEC	ICGC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7329
p.P349L	DO47317	SKCM	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1944
p.S366L	DO47569	SKCM	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1389
p.R344W	DO38795	STAD	ICGC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.0556
p.E506K	SIDM00353	Other Sarcomas	GDSC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation rewiring degron network	0.1111
p.E506K	SIDM00353	Other Sarcomas	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.25
p.E506K	SIDM00767	Small Cell Lung Carcinoma	GDSC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation rewiring degron network	0.1111
p.E506K	SIDM00767	Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.25
p.E506K	RKN	ovary	COSMIC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation rewiring degron network	0.1111
p.E506K	RKN	ovary	COSMIC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.25
p.E506K	NCI-H187	lung	COSMIC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation rewiring degron network	0.1111
p.E506K	NCI-H187	lung	COSMIC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.25
p.S435R	SIDM00389	B-Cell Non-Hodgkin's Lymphoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.0556
p.S435R	SIDM00389	B-Cell Non-Hodgkin's Lymphoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1389
p.I413T	SIDM01090	Colorectal Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00454	Rhabdomyosarcoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00656	Burkitt's Lymphoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00087	Plasma Cell Myeloma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00447	B-Lymphoblastic Leukemia	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM01112	Osteosarcoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00650	Small Cell Lung Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00694	Other Solid Cancers	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00879	Breast Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00971	Breast Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00493	Other Solid Cancers	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00875	Breast Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00844	Burkitt's Lymphoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM01133	Other Solid Cancers	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM01681	Non-Cancerous	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM01318	Hepatocellular Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM00641	Burkitt's Lymphoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.I413T	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.2222
p.R433Q	SIDM00969	Ovarian Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM00969	Ovarian Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM00654	Small Cell Lung Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM00654	Small Cell Lung Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM00046	Non-Small Cell Lung Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM00046	Non-Small Cell Lung Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM00793	Burkitt's Lymphoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM00793	Burkitt's Lymphoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM00760	Small Cell Lung Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM00760	Small Cell Lung Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM00785	Acute Myeloid Leukemia	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM00785	Acute Myeloid Leukemia	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM01318	Hepatocellular Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM01318	Hepatocellular Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM01664	Prostate Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM01664	Prostate Carcinoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.R433Q	SIDM01525	Acute Myeloid Leukemia	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R433Q	SIDM01525	Acute Myeloid Leukemia	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.1944
p.H500Y	SIDM00454	Rhabdomyosarcoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00447	B-Lymphoblastic Leukemia	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM01112	Osteosarcoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00650	Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00694	Other Solid Cancers	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00879	Breast Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00052	Esophageal Squamous Cell Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00971	Breast Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00493	Other Solid Cancers	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00875	Breast Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00844	Burkitt's Lymphoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM01133	Other Solid Cancers	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM01681	Non-Cancerous	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM01318	Hepatocellular Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM00641	Burkitt's Lymphoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.H500Y	SIDM01605	Non-Small Cell Lung Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation rewiring degron network	0.0833
p.P509L	SIDM00923	Cervical Carcinoma	GDSC	PPSY	ITCH	509:512	Mutation altering degron motif	0.7582
p.P509L	Ca-Ski	cervix	COSMIC	PPSY	ITCH	509:512	Mutation altering degron motif	0.7582
p.P438S	SIDM00337	Melanoma	GDSC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0556
p.P438S	ACH-000450	Skin Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0556
p.P438S	ACH-000884	Skin Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0556
p.P438S	M14	skin	COSMIC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0556
p.P438S	MEL-HO	skin	COSMIC	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0556
p.Q352H	SIDM00210	Ovarian Carcinoma	GDSC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.2778
p.Q352H	SIDM00673	Breast Carcinoma	GDSC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.2778
p.K508R	SIDM01120	Other Solid Cancers	GDSC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation substituting flanking lysine	0.2778
p.K508R	ACH-002174	Lung Cancer	CCLE	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation substituting flanking lysine	0.2778
p.K508R	NCI-H720	lung	COSMIC	SLDITPGK	DEG_SCF_SKP2-CKS1_1	514:521	Mutation substituting flanking lysine	0.2778
p.G367R	SIDM00282	Colorectal Carcinoma	GDSC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367R	ACH-000998	Colon/Colorectal Cancer	CCLE	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.G367R	CW-2	large intestine	COSMIC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1111
p.D417Y	SIDM00344	Non-Small Cell Lung Carcinoma	GDSC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.6214
p.D417Y	ACH-000596	Lung Cancer	CCLE	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.6214
p.D417Y	LCLC-97TM1	lung	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.6214
p.R418S	ACH-000215	Brain Cancer	CCLE	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7427
p.P437S	ACH-001566	Skin Cancer	CCLE	VPSSS	DEG_SPOP_SBC_1	424:428	Mutation rewiring degron network	0.0833
p.G409R	NCI-H748	lung	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.1111
p.R418Q	SUIT-2	pancreas	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7329
p.R418Q	SNU-398	liver	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7329
p.R418Q	KMOE-2	haematopoietic and lymphoid tissue	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7329
p.R418Q	PC-14	lung	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7329
p.K419R	NCI-H720	lung	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7237
p.P349S	M14	skin	COSMIC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1944
p.P349S	MEL-HO	skin	COSMIC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.1944
p.P420L	Ca-Ski	cervix	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7582
p.E417K	NCI-H187	lung	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7022
p.E417K	RKN	ovary	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation altering degron motif	0.7022
p.R407C	SU-DHL-5	haematopoietic and lymphoid tissue	COSMIC	DRDSLSDVP	DEG_APCC_DBOX_1	417:425	Mutation rewiring degron network	0.0556
p.R353C	SW626	ovary	COSMIC	LTPIPS	DEG_SCF_FBW7_1	354:359	Mutation rewiring degron network	0.3056

DegronMD: protein-targeted degradation, mutation and drug response to degrons

ILDR1

UniProt ID: Q86SU0

Entrez ID: 286676

Protein name: Immunoglobulin-like domain-containing receptor 1 (Angulin-2)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for ILDR1 in