DegronMD - Q96BU1(S100PBP)

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.N282K	TCGA-06-1802	GBM	TCGA	VVSTS	DEG_SPOP_SBC_1	270:274	Mutation rewiring degron network	0.1111
p.S101A	TCGA-AA-3977	COAD	TCGA	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6477
p.S101A	DO8730	COAD	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6477
p.N99K	TCGA-CA-6717	COAD	TCGA	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6918
p.N99K	DO8264	COAD	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6918
p.P111H	TCGA-CG-5723	STAD	TCGA	NSSYSLGP	CBL_PTK	99:106	Mutation rewiring degron network	0.1944
p.P111H	DO38376	STAD	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation rewiring degron network	0.1944
p.K305N	TCGA-JW-A5VL	CESC	TCGA	TKTRTNVPTF	DEG_COP1_1	304:313	Mutation altering degron motif	0.5806
p.R96L	TCGA-L9-A5IP	LUAD	TCGA	NSSYSLGP	CBL_PTK	99:106	Mutation rewiring degron network	0.25
p.R96L	DO49873	LUAD	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation rewiring degron network	0.25
p.K304N	DO49976	CESC	ICGC	TKTRTNVPTF	DEG_COP1_1	304:313	Mutation altering degron motif	0.6918
p.P310L	DO228542	GACA	ICGC	TKTRTNVPTF	DEG_COP1_1	304:313	Mutation altering degron motif	0.7582
p.N281K	DO12100	GBM	ICGC	VVSTS	DEG_SPOP_SBC_1	270:274	Mutation rewiring degron network	0.1389
p.T94S	DO23262	LINC	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation blocking phosphorylation signal	0.6389
p.G105E	DO228829	MALY	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6087
p.G105E	SIDM00694	Other Solid Cancers	GDSC	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6087
p.G105E	SIDM00785	Acute Myeloid Leukemia	GDSC	NSSYSLGP	CBL_PTK	99:106	Mutation altering degron motif	0.6087
p.L113F	DO222708	MELA	ICGC	NSSYSLGP	CBL_PTK	99:106	Mutation rewiring degron network	0.1389
p.Q322K	DO229257	THCA	ICGC	TKTRTNVPTF	DEG_COP1_1	304:313	Mutation blocking ubiquitination signal	0.5278
p.R96Q	SIDM00673	Breast Carcinoma	GDSC	NSSYSLGP	CBL_PTK	99:106	Mutation rewiring degron network	0.25
p.Q303H	ACH-000586	Lung Cancer	CCLE	TKTRTNVPTF	DEG_COP1_1	304:313	Mutation rewiring degron network	0.3056
p.Q303H	NCI-H1876	lung	COSMIC	TKTRTNVPTF	DEG_COP1_1	304:313	Mutation rewiring degron network	0.3056

Kaplan plot for S100PBP in

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*NOTE: the Kaplan plots were collected from OncoLnc

DegronMD: protein-targeted degradation, mutation and drug response to degrons

S100PBP

UniProt ID: Q96BU1

Entrez ID: 64766

Protein name: S100P-binding protein (S100P-binding protein Riken)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for S100PBP in