p.P3696L | TCGA-18-3409 | LUSC | TCGA | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1667 |
p.P3696L | DO26444 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1667 |
p.T256I | TCGA-19-5956 | GBM | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0556 |
p.T256I | DO13863 | GBM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0556 |
p.G48C | TCGA-33-6738 | LUSC | TCGA | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.G48C | TCGA-B5-A3FC | UCEC | TCGA | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.G48C | DO26516 | LUSC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.G48C | DO41871 | UCEC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.S669Y | TCGA-37-A5EM | LUSC | TCGA | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation altering degron motif | 0.6009 |
p.S669Y | DO223719 | LUSC | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation altering degron motif | 0.6009 |
p.E279K | TCGA-86-7711 | LUAD | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.E279K | TCGA-EE-A3AG | SKCM | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.E279K | TCGA-FS-A1ZK | SKCM | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.E279K | DO25717 | LUAD | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.E279K | DO37474 | SKCM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.E279K | DO37471 | SKCM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.S354C | TCGA-98-8022 | LUSC | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.2222 |
p.S354C | DO26934 | LUSC | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.2222 |
p.S272T | TCGA-A6-3809 | COAD | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation blocking phosphorylation signal | 0.7222 |
p.S272T | DO8722 | COAD | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation blocking phosphorylation signal | 0.7222 |
p.G496V | TCGA-AB-2826 | LAML | TCGA | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0556 |
p.G496V | DO21833 | LAML | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0556 |
p.V3715F | TCGA-B0-4698 | KIRC | TCGA | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.0833 |
p.V3715F | DO20368 | KIRC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.0833 |
p.L34F | TCGA-B5-A0JY | UCEC | TCGA | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.0833 |
p.L34F | DO234377 | ESAD | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.0833 |
p.L34F | DO43041 | UCEC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.0833 |
p.L353V | TCGA-B7-5818 | STAD | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.L353V | DO38883 | STAD | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.T343I | TCGA-BF-A5ER | SKCM | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.T343I | TCGA-Z2-A8RT | SKCM | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.T343I | DO51301 | SKCM | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.T343I | DO219454 | SKCM | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.G2124E | TCGA-BH-A0HW | BRCA | TCGA | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | DO1960 | BRCA | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM01040 | Ovarian Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00577 | Neuroblastoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00555 | Glioblastoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00581 | Glioblastoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00360 | Other Solid Cancers | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00054 | Pancreatic Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00498 | Colorectal Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00567 | Other Solid Cancers | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.G2124E | SIDM00613 | Glioblastoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.S272C | TCGA-C5-A905 | CESC | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation blocking phosphorylation signal | 0.7222 |
p.S272C | DO49918 | CESC | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation blocking phosphorylation signal | 0.7222 |
p.G271C | TCGA-CM-6171 | COAD | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.3056 |
p.G271C | DO8151 | COAD | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.3056 |
p.S656C | TCGA-CQ-6221 | HNSC | TCGA | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S656C | DO14622 | HNSC | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.Q337E | TCGA-CQ-6222 | HNSC | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.0833 |
p.Q337E | DO14433 | HNSC | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.0833 |
p.P3714H | TCGA-D5-6928 | COAD | TCGA | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.P3714H | DO7776 | COAD | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.G519E | TCGA-DA-A3F3 | SKCM | TCGA | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0833 |
p.G519E | DO37607 | SKCM | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0833 |
p.G519E | SIDM00007 | Other Solid Cancers | GDSC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0833 |
p.G519E | ACH-001550 | Skin Cancer | CCLE | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0833 |
p.G519E | MCC13 | skin | COSMIC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.0833 |
p.T36S | TCGA-DF-A2KV | UCEC | TCGA | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1389 |
p.T36S | DO219771 | UCEC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1389 |
p.S509P | TCGA-E6-A1LX | UCEC | TCGA | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation altering degron motif | 0.6752 |
p.S509P | DO41020 | UCEC | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation altering degron motif | 0.6752 |
p.S350L | TCGA-EE-A29M | SKCM | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation altering degron motif | 0.7667 |
p.S350L | DO37404 | SKCM | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation altering degron motif | 0.7667 |
p.S669F | TCGA-EE-A3JA | SKCM | TCGA | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation altering degron motif | 0.6871 |
p.S669F | DO47625 | SKCM | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation altering degron motif | 0.6871 |
p.L2129I | TCGA-EK-A3GJ | CESC | TCGA | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1944 |
p.L2129I | DO49962 | CESC | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1944 |
p.L1489V | TCGA-EK-A3GK | CESC | TCGA | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.3056 |
p.L1489V | DO49964 | CESC | ICGC | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.3056 |
p.P2144H | TCGA-EO-A22U | UCEC | TCGA | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1667 |
p.P2144H | DO43755 | UCEC | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1667 |
p.G275E | TCGA-ER-A193 | SKCM | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1944 |
p.G275E | DO47368 | SKCM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1944 |
p.S261L | TCGA-FD-A43X | BLCA | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1944 |
p.S261L | DO44067 | BLCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1944 |
p.G48A | TCGA-FJ-A3Z7 | BLCA | TCGA | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.G48A | DO463 | BLCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.E504Q | TCGA-IR-A3LK | CESC | TCGA | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.2778 |
p.E504Q | DO44299 | CESC | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.2778 |
p.L2145F | TCGA-IR-A3LL | CESC | TCGA | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1389 |
p.L2145F | DO44362 | CESC | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1389 |
p.L353F | TCGA-L9-A8F4 | LUAD | TCGA | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.L353F | DO49876 | LUAD | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.25 |
p.T265P | TCGA-MV-A51V | BLCA | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.3056 |
p.T265P | DO474 | BLCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.3056 |
p.L274V | TCGA-RA-A741 | CESC | TCGA | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.2222 |
p.L274V | DO49013 | CESC | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.2222 |
p.V655I | TCGA-VS-A8EH | CESC | TCGA | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.0833 |
p.V655I | DO222574 | BTCA | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.0833 |
p.V655I | DO51620 | CESC | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.0833 |
p.V655I | DO228088 | EOPC | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.0833 |
p.V655I | DO234199 | ESAD | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.0833 |
p.E273K | DO8119 | COAD | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.25 |
p.N266K | DO230334 | COCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO229010 | COCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO229013 | COCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO229016 | COCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO229003 | COCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO229005 | COCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO229346 | LAML | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.N266K | DO231160 | LUSC | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6918 |
p.A41P | DO230334 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.A41P | DO229010 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.A41P | DO229013 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.A41P | DO229016 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.A41P | DO229003 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.A41P | DO229005 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.A41P | DO234285 | ESAD | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.S3707T | DO224761 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707T | DO222881 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707T | DO229010 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707T | DO52341 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707T | DO52391 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.T3710A | DO224761 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.2222 |
p.T3710A | DO222881 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.2222 |
p.T3710A | DO229010 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.2222 |
p.T3710A | DO52341 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.2222 |
p.H3709Q | DO224739 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229010 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO52341 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO52391 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO232257 | PBCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO232552 | PBCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO232665 | PBCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229184 | THCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229257 | THCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229264 | THCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229268 | THCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229201 | THCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.H3709Q | DO229248 | THCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.25 |
p.I3701S | DO224739 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.I3701S | DO229010 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.I3701S | DO228827 | LICA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.I3701S | DO52341 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.I3701S | DO52391 | LUSC | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.V1502A | DO222585 | COCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.1111 |
p.A3694V | DO229010 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.Q3693H | DO229010 | COCA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.0833 |
p.Q3693H | SIDM00377 | Other Sarcomas | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.0833 |
p.T2137A | DO229013 | COCA | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7139 |
p.T2137A | DO229016 | COCA | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7139 |
p.T2137A | DO229003 | COCA | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7139 |
p.P336L | DO234313 | ESAD | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.0556 |
p.N498D | DO233797 | GACA | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.1111 |
p.K39R | DO233941 | GACA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation substituting flanking lysine | 0.3333 |
p.R354L | DO20936 | KIRP | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.2222 |
p.R354L | DO47374 | SKCM | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.2222 |
p.P3696S | DO229346 | LAML | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1667 |
p.S675P | DO49666 | LIAD | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1944 |
p.T508A | DO228234 | LICA | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation altering degron motif | 0.7139 |
p.W669R | DO228574 | LICA | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation altering degron motif | 0.8634 |
p.S3705A | DO228832 | LICA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation altering degron motif | 0.7588 |
p.S3705A | DO228856 | LICA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation altering degron motif | 0.7588 |
p.T280A | DO50770 | LICA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0556 |
p.I55N | DO231569 | LINC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1111 |
p.G339D | DO26987 | LUSC | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.1389 |
p.E671K | DO223719 | LUSC | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.3056 |
p.P3714S | DO220889 | MELA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.P3714S | SIDM00140 | Melanoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.P3714S | ACH-000968 | Skin Cancer | CCLE | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.P3714S | COLO-792 | skin | COSMIC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.S3703F | DO222632 | MELA | ICGC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation altering degron motif | 0.6871 |
p.R45G | DO232846 | NACA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation altering degron motif | 0.7568 |
p.G265V | DO232852 | NACA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.3056 |
p.L516F | DO232861 | NACA | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.1667 |
p.P267Q | DO233297 | NACA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.7035 |
p.V48M | DO233299 | NACA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.3056 |
p.S350T | DO51511 | PACA | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation altering degron motif | 0.6005 |
p.N676D | DO35424 | PACA | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1667 |
p.D355E | DO229113 | PRAD | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.1944 |
p.R41H | DO51407 | PRAD | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.P33S | DO218847 | SKCA | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.0556 |
p.T273A | DO229502 | SKCA | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.25 |
p.Q257K | DO37778 | SKCM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.P267T | DO37703 | SKCM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.7031 |
p.E280K | DO37430 | SKCM | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0556 |
p.R357Q | DO47320 | SKCM | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.1389 |
p.T53I | DO51276 | SKCM | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1667 |
p.T53I | DO43755 | UCEC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1667 |
p.W338S | DO48005 | STAD | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.1111 |
p.F272V | DO47767 | STAD | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation blocking phosphorylation signal | 0.7222 |
p.P513R | DO229253 | THCA | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.25 |
p.S2136L | DO229272 | THCA | ICGC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7667 |
p.R350C | DO229216 | THCA | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation altering degron motif | 0.8301 |
p.R41C | DO40828 | UCEC | ICGC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.2778 |
p.S509R | DO41847 | UCEC | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation altering degron motif | 0.7427 |
p.R354Q | DO42608 | UCEC | ICGC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.2222 |
p.E266K | DO43907 | UCEC | ICGC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.7022 |
p.N676K | DO43755 | UCEC | ICGC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1667 |
p.L506M | DO41199 | UCEC | ICGC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation altering degron motif | 0.711 |
p.T40I | SIDM02021 | Esophageal Carcinoma | GDSC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.25 |
p.L3713P | SIDM00967 | Ovarian Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00087 | Plasma Cell Myeloma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00264 | Ewing's Sarcoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00690 | Head and Neck Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM01112 | Osteosarcoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00650 | Small Cell Lung Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00879 | Breast Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00052 | Esophageal Squamous Cell Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00493 | Other Solid Cancers | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM01681 | Non-Cancerous | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00720 | Mesothelioma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00808 | Burkitt's Lymphoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.L3713P | SIDM00628 | Breast Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1389 |
p.T3710I | SIDM00967 | Ovarian Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.2222 |
p.Q337P | SIDM01117 | Small Cell Lung Carcinoma | GDSC | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.0833 |
p.S3707A | SIDM00426 | Rhabdomyosarcoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707A | SIDM00376 | B-Lymphoblastic Leukemia | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707A | SIDM01135 | Pancreatic Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707A | SIDM00443 | B-Cell Non-Hodgkin's Lymphoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707A | SIDM01085 | Bladder Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707A | RT4 | urinary tract | COSMIC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.S3707A | NU-DUL-1 | haematopoietic and lymphoid tissue | COSMIC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.3056 |
p.A3694T | SIDM00602 | Gastric Carcinoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.A3694T | IM-95 | stomach | COSMIC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1111 |
p.T659A | SIDM00120 | Prostate Carcinoma | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1944 |
p.T659A | ACH-000979 | Prostate Cancer | CCLE | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1944 |
p.T659A | DU-145 | prostate | COSMIC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1944 |
p.P277S | SIDM01175 | Other Sarcomas | GDSC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1389 |
p.P277S | ACH-002309 | Sarcoma | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1389 |
p.P277S | SW684 | soft tissue | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1389 |
p.T661N | SIDM00789 | Colorectal Carcinoma | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.25 |
p.T661N | ACH-000997 | Colon/Colorectal Cancer | CCLE | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.25 |
p.T661N | HCT-15 | large intestine | COSMIC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.25 |
p.P2146S | SIDM00007 | Other Solid Cancers | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1111 |
p.V2147D | SIDM00356 | Non-Small Cell Lung Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.V2147D | SIDM00237 | Non-Small Cell Lung Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.V2147D | ACH-000482 | Lung Cancer | CCLE | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.V2147D | PC-14 | lung | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.V2147D | RERF-LC-KJ | lung | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.S656Y | SIDM00356 | Non-Small Cell Lung Carcinoma | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S656Y | SIDM00354 | Squamous Cell Lung Carcinoma | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S656Y | SIDM00287 | B-Lymphoblastic Leukemia | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S656Y | SIDM00251 | Gastric Carcinoma | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S656Y | SIDM00247 | Gastric Carcinoma | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S656Y | SIDM01498 | Acute Myeloid Leukemia | GDSC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.V266M | SIDM00282 | Colorectal Carcinoma | GDSC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.7208 |
p.V266M | ACH-000998 | Colon/Colorectal Cancer | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.7208 |
p.V266M | CW-2 | large intestine | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.7208 |
p.P2128H | SIDM00687 | Gastric Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1667 |
p.P2128H | ACH-000793 | Gastric Cancer | CCLE | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1667 |
p.P2128H | KATOIII | stomach | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1667 |
p.P2144S | SIDM00596 | Endometrial Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1667 |
p.T267K | SIDM00114 | Non-Small Cell Lung Carcinoma | GDSC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6195 |
p.T267K | H513 | pleura | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation altering degron motif | 0.6195 |
p.V2147F | SIDM00653 | Small Cell Lung Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.V2147F | ACH-000514 | Lung Cancer | CCLE | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.V2147F | NCI-H1092 | lung | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0833 |
p.G2140S | SIDM01088 | Endometrial Carcinoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.2778 |
p.G2140S | ACH-000965 | Endometrial/Uterine Cancer | CCLE | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.2778 |
p.G2140S | RL95-2 | endometrium | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.2778 |
p.P3712S | SIDM00574 | Glioblastoma | GDSC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1667 |
p.P3712S | no-10 | central nervous system | COSMIC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.1667 |
p.T2127N | SIDM00863 | Burkitt's Lymphoma | GDSC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1389 |
p.T2127N | ACH-001064 | Lymphoma | CCLE | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1389 |
p.T2127N | EB2 | haematopoietic and lymphoid tissue | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.1389 |
p.T499A | SIDM01611 | Endometrial Carcinoma | GDSC | PSTST | DEG_SPOP_SBC_1 | 506:510 | Mutation rewiring degron network | 0.1389 |
p.F279Y | ACH-000004 | Leukemia | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279Y | ACH-000005 | Leukemia | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279Y | HEL | haematopoietic and lymphoid tissue | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279Y | CMK | haematopoietic and lymphoid tissue | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279I | ACH-000004 | Leukemia | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279I | ACH-000005 | Leukemia | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279I | CMK | haematopoietic and lymphoid tissue | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.F279I | HEL | haematopoietic and lymphoid tissue | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.0833 |
p.Y278C | ACH-000213 | Pancreatic Cancer | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1111 |
p.Y278C | HuP-T4 | pancreas | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1111 |
p.S1496A | ACH-000738 | Brain Cancer | CCLE | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.2778 |
p.S1496A | GB-1 | central nervous system | COSMIC | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.2778 |
p.Q52L | ACH-000920 | Leukemia | CCLE | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1944 |
p.Q52L | CML-T1 | haematopoietic and lymphoid tissue | COSMIC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1944 |
p.G1500S | ACH-000966 | Ovarian Cancer | CCLE | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.1667 |
p.P2134T | ACH-000970 | Colon/Colorectal Cancer | CCLE | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7031 |
p.P2134T | SNU-C5 | large intestine | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7031 |
p.D678N | ACH-000971 | Colon/Colorectal Cancer | CCLE | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.D678N | HCT-116 | large intestine | COSMIC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.S1482Y | ACH-000997 | Colon/Colorectal Cancer | CCLE | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.1111 |
p.T656A | ACH-000999 | Colon/Colorectal Cancer | CCLE | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.T656A | SNU-1040 | large intestine | COSMIC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1111 |
p.V260A | ACH-000999 | Colon/Colorectal Cancer | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1667 |
p.V260A | SNU-1040 | large intestine | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.1667 |
p.R263H | ACH-001350 | Thyroid Cancer | CCLE | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation substituting flanking lysine | 0.3611 |
p.R263H | HTC-C3 | thyroid | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation substituting flanking lysine | 0.3611 |
p.R354W | ACH-001390 | Breast Cancer | CCLE | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.2222 |
p.C345F | ACH-002464 | Non-Cancerous | CCLE | PVTTS | DEG_SPOP_SBC_1 | 346:350 | Mutation rewiring degron network | 0.3056 |
p.R264W | CCRF-CEM | haematopoietic and lymphoid tissue | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.2778 |
p.P3698H | OVCA420 | ovary | COSMIC | PSSSS | DEG_SPOP_SBC_1 | 3702:3706 | Mutation rewiring degron network | 0.2222 |
p.G39R | RKO | large intestine | COSMIC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation substituting flanking lysine | 0.3333 |
p.D1485E | EC-GI-10 | oesophagus | COSMIC | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation rewiring degron network | 0.1944 |
p.P2134L | SW620 | large intestine | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7582 |
p.P2134L | Farage | haematopoietic and lymphoid tissue | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation altering degron motif | 0.7582 |
p.R271H | HDQ-P1 | breast | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation rewiring degron network | 0.3056 |
p.S1493G | NCI-H2196 | lung | COSMIC | PVTST | DEG_SPOP_SBC_1 | 1490:1494 | Mutation altering degron motif | 0.6993 |
p.A658V | MDA-MB-330 | breast | COSMIC | VTTPGSS | DEG_SCF_FBW7_1 | 664:670 | Mutation rewiring degron network | 0.1667 |
p.L272F | NCI-H196 | lung | COSMIC | VTTST | DEG_SPOP_SBC_1 | 266:270 | Mutation blocking phosphorylation signal | 0.7222 |
p.G2124V | SiHa | cervix | COSMIC | PSSTS | DEG_SPOP_SBC_1 | 2134:2138 | Mutation rewiring degron network | 0.0556 |
p.F55C | PE/CA-PJ15 | upper aerodigestive tract | COSMIC | PVTST | DEG_SPOP_SBC_1 | 43:47 | Mutation rewiring degron network | 0.1111 |