DegronMD - Q9UKV0(HDAC9)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.V307F	TCGA-17-Z022	LUAD	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1667
p.S615Y	TCGA-17-Z030	LUAD	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.712
p.E263G	TCGA-17-Z031	LUAD	TCGA	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.25
p.G277V	TCGA-34-5240	LUSC	TCGA	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1389
p.M306I	TCGA-66-2759	LUSC	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1944
p.R628C	TCGA-97-7552	LUAD	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1111
p.T612S	TCGA-A5-A0G1	UCEC	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.7116
p.P622S	TCGA-AG-3893	READ	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2778
p.R628H	TCGA-AP-A1DV	UCEC	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1111
p.R628H	TCGA-VQ-A91D	STAD	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1111
p.P616S	TCGA-AR-A251	BRCA	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.P616S	SIDM00839	Colorectal Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.P616S	ACH-000950	Colon/Colorectal Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.P616S	LoVo	large intestine	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.L386F	TCGA-AX-A3G3	UCEC	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation substituting flanking lysine	0.1944
p.V307D	TCGA-C9-A47Z	HNSC	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1667
p.A617T	TCGA-CG-4442	STAD	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.7139
p.A625E	TCGA-CM-5861	COAD	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.E387D	TCGA-CN-6021	HNSC	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0556
p.P382H	TCGA-DA-A1I1	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1944
p.Y371C	TCGA-DD-AAE7	LIHC	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2778
p.R311H	TCGA-E6-A1LX	UCEC	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0556
p.R311H	SIDM00527	Colorectal Carcinoma	GDSC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0556
p.R311H	MDST8	large intestine	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0556
p.S256L	TCGA-EB-A41A	SKCM	TCGA	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation substituting flanking lysine	0.1667
p.G369V	TCGA-EE-A2GT	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2222
p.G369V	SIDM00144	Non-Small Cell Lung Carcinoma	GDSC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2222
p.G369V	NCI-H460	lung	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2222
p.S615F	TCGA-EE-A2MD	SKCM	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.7982
p.S615F	TCGA-EE-A2MS	SKCM	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.7982
p.G364C	TCGA-EE-A2MQ	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0833
p.R260Q	TCGA-EE-A3JD	SKCM	TCGA	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1667
p.S280L	TCGA-EK-A2PG	CESC	TCGA	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.0556
p.A303V	TCGA-FS-A1ZW	SKCM	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.2778
p.P366S	TCGA-FU-A23L	CESC	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1389
p.P366S	TCGA-GF-A6C9	SKCM	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1389
p.R628S	TCGA-FV-A496	LIHC	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1111
p.S295L	TCGA-FW-A3R5	SKCM	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7667
p.S267F	TCGA-GS-A9TZ	DLBC	TCGA	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation altering degron motif	0.6871
p.S380G	TCGA-IB-7651	PAAD	TCGA	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.25
p.S295P	TCGA-L5-A43J	ESCA	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.6752
p.P298S	TCGA-L5-A88V	ESCA	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.6752
p.T300I	TCGA-LN-A4A3	ESCA	TCGA	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7078
p.R607H	TCGA-VQ-A8P2	STAD	TCGA	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.L383V	DO49797	BLCA	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1667
p.P613S	DO5724	BRCA	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.P613S	LoVo	large intestine	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.A622E	DO7918	COAD	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2778
p.L290M	DO8634	COAD	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.2222
p.Q376R	DO227985	COCA	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.7329
p.L304V	DO222760	COCA	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.25
p.P307L	DO50374	ESAD	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1667
p.R280H	DO234239	ESAD	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.0556
p.R280H	DO41020	UCEC	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.0556
p.R280H	MDST8	large intestine	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.0556
p.L266F	DO233130	GACA	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation altering degron motif	0.6981
p.P300L	DO233621	GACA	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7582
p.G387E	DO233747	GACA	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0556
p.A385T	DO13863	GBM	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.V276D	DO44423	HNSC	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1667
p.G387V	DO16955	KIRC	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0556
p.S298F	DO228983	LICA	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7982
p.R625S	DO44966	LIHC	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.R625C	DO25050	LUAD	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.D286Y	DO26444	LUSC	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1111
p.M275I	DO27326	LUSC	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1944
p.A366V	DO220851	MELA	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1389
p.D624N	DO220913	MELA	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.S612F	DO222434	MELA	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6871
p.S612F	DO37567	SKCM	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6871
p.S612F	DO37851	SKCM	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6871
p.N261D	DO222775	MELA	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1944
p.E273K	DO222843	MELA	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.25
p.P619S	DO36640	READ	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6752
p.P300S	DO37623	SKCM	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.6752
p.A272V	DO37519	SKCM	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.2778
p.S264L	DO37406	SKCM	ICGC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.2778
p.E375K	DO50297	SKCM	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.7022
p.G305V	DO47374	SKCM	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.2222
p.A614T	DO38380	STAD	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6028
p.R625H	DO51783	STAD	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.R625H	DO43186	UCEC	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.R604H	DO51761	STAD	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1111
p.L383I	DO229213	THCA	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1667
p.A366T	DO43186	UCEC	ICGC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1389
p.M288I	DO41235	UCEC	ICGC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1667
p.T609S	DO42472	UCEC	ICGC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.25
p.M261V	SIDM00845	Burkitt's Lymphoma	GDSC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1944
p.V289F	SIDM00231	Kidney Carcinoma	GDSC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1944
p.V289F	NCC010	kidney	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1944
p.R611S	SIDM00548	Squamous Cell Lung Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.3056
p.R611S	ACH-000769	Lung Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.3056
p.R611S	LK-2	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.3056
p.A625V	SIDM01093	Cervical Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	SIDM00383	Gastric Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	SIDM01029	Esophageal Squamous Cell Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	ACH-000556	Cervical Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	ACH-000873	Esophageal Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	ACH-002198	Gastric Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	SCH	stomach	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	SiHa	cervix	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.A625V	KYSE-270	oesophagus	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1944
p.V609I	SIDM00681	Colorectal Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.25
p.V609I	ACH-000252	Colon/Colorectal Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.25
p.V609I	LS-1034	large intestine	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.25
p.M261I	SIDM00585	Hepatocellular Carcinoma	GDSC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1944
p.M261I	HuH-7	liver	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1944
p.E304K	SIDM00251	Gastric Carcinoma	GDSC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.25
p.A617V	SIDM00651	Non-Small Cell Lung Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6936
p.A617V	ACH-000980	Lung Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6936
p.A617V	NCI-H1155	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.6936
p.P376L	SIDM00429	B-Lymphoblastic Leukemia	GDSC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.7582
p.D627E	SIDM00365	Small Cell Lung Carcinoma	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1389
p.D627E	SBC-1	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1389
p.H381Q	SIDM00640	Mesothelioma	GDSC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2222
p.H381Q	MSTO-211H	pleura	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2222
p.P624L	SIDM00145	T-Lymphoblastic Leukemia	GDSC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.P624L	ACH-001127	Leukemia	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.P624L	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.P301R	SIDM00750	Non-Small Cell Lung Carcinoma	GDSC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7512
p.P301R	NCI-H1568	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7512
p.H301Q	ACH-000335	Lung Cancer	CCLE	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7582
p.H301Q	MSTO-211H	pleura	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7582
p.G289V	ACH-000463	Lung Cancer	CCLE	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1944
p.G289V	NCI-H460	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1944
p.R365C	ACH-000643	Breast Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.R365C	HDQ-P1	breast	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.E272Q	ACH-001127	Leukemia	CCLE	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.2778
p.E272Q	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.2778
p.S374C	ACH-001402	Cervical Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.7541
p.S374C	SW756	cervix	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.7541
p.R365H	ACH-001490	Lung Cancer	CCLE	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.R365H	COR-L321	NS	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.P629L	ACH-001838	Bile Duct Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.0833
p.D624E	ACH-002196	Lung Cancer	CCLE	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.D624E	SBC-1	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.H378Q	MSTO-211H	pleura	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.3056
p.G374A	JHH-7	liver	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.754
p.M258I	HuH-7	liver	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1111
p.A622V	SiHa	cervix	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2778
p.A622V	KYSE-270	oesophagus	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2778
p.A622V	SCH	stomach	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2778
p.L269I	NCI-H1666	lung	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation altering degron motif	0.7174
p.V286F	NCC010	kidney	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1111
p.R365Q	HCC2998	large intestine	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.P298R	NCI-H1568	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7512
p.A614V	NCI-H1155	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.5825
p.S285Y	SNU-81	large intestine	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0833
p.R264H	MDST8	large intestine	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.2778
p.R267H	MDST8	large intestine	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation altering degron motif	0.8244
p.R306H	MDST8	large intestine	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1944
p.V606I	LS-1034	large intestine	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1667
p.R308H	MDST8	large intestine	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1389
p.L297I	NCI-H1666	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.7174
p.P296R	NCI-H1568	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.6401
p.S298Y	SNU-81	large intestine	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.712
p.R608S	LK-2	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.2222
p.G366V	NCI-H460	lung	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1389
p.H376Q	MSTO-211H	pleura	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation altering degron motif	0.7582
p.P621L	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.3056
p.R378Q	HCC2998	large intestine	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.3056
p.L266I	NCI-H1666	lung	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation altering degron motif	0.7174
p.V284F	NCC010	kidney	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0556
p.P257R	NCI-H1568	lung	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.0833
p.G387A	JHH-7	liver	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0556
p.E308Q	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1389
p.L310I	NCI-H1666	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0833
p.V273F	NCC010	kidney	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.25
p.R385K	MFE-319	endometrium	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.E305Q	MOLT-4	haematopoietic and lymphoid tissue	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.2222
p.G371A	JHH-7	liver	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.2778
p.S363T	CW-2	large intestine	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0556
p.H613Y	LU-135	lung	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation altering degron motif	0.7229
p.R626Q	OC-314	ovary	COSMIC	SPAASVLPH	DEG_SIAH_1	612:620	Mutation rewiring degron network	0.1667
p.P285R	NCI-H1568	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.0833
p.P270R	NCI-H1568	lung	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation altering degron motif	0.7512
p.H365Q	MSTO-211H	pleura	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.1111
p.S378T	CW-2	large intestine	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.3056
p.V258F	NCC010	kidney	COSMIC	VSSSS	DEG_SPOP_SBC_1	266:270	Mutation rewiring degron network	0.1111
p.L308I	NCI-H1666	lung	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation rewiring degron network	0.1389
p.R295H	MDST8	large intestine	COSMIC	LPPTPHAE	DEG_SCF_FBW7_2	294:301	Mutation altering degron motif	0.8244
p.G364V	NCI-H460	lung	COSMIC	PASSS	DEG_SPOP_SBC_1	373:377	Mutation rewiring degron network	0.0833

DegronMD: protein-targeted degradation, mutation and drug response to degrons

HDAC9

UniProt ID: Q9UKV0

Entrez ID: 9734

Protein name: Histone deacetylase 9 (HD9) (EC 3.5.1.98) (Histone deacetylase 7B) (HD7) (HD7b) (Histone deacetylase-related protein) (MEF2-interacting transcription repressor MITR)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for HDAC9 in