DegronMD - Q9UL68(MYT1L)

Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.E840G	TCGA-18-3409	LUSC	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.E840G	DO26444	LUSC	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.E635G	TCGA-24-1845	OV	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.1667
p.E635G	DO29920	OV	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.1667
p.Y639S	TCGA-33-4582	LUSC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.0556
p.Y639S	DO26698	LUSC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.0556
p.G552C	TCGA-37-4141	LUSC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.76
p.G552C	DO26862	LUSC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.76
p.P855R	TCGA-50-5045	LUAD	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1667
p.P855R	DO23723	LUAD	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1667
p.T626S	TCGA-52-7812	LUSC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7116
p.T626S	DO27067	LUSC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7116
p.R556S	TCGA-77-8133	LUSC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7427
p.R556S	DO27039	LUSC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7427
p.N631I	TCGA-98-8022	LUSC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.2778
p.N631I	DO26934	LUSC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.2778
p.T627M	TCGA-A6-5659	COAD	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	TCGA-DF-A2KU	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	TCGA-FI-A2D0	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	TCGA-RD-A8NB	STAD	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	DO9860	COAD	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	DO50142	STAD	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	DO223286	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T627M	DO43891	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7423
p.T554M	TCGA-AA-3864	COAD	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7423
p.T554M	TCGA-XF-A9SG	BLCA	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7423
p.T554M	DO51912	BLCA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7423
p.T554M	DO8490	COAD	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7423
p.T554M	DO222285	GACA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7423
p.T554M	DO233843	GACA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7423
p.P551L	TCGA-AJ-A3BH	UCEC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.6471
p.P551L	DO225337	BRCA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.6471
p.P551L	DO41638	UCEC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.6471
p.P551L	ACH-000941	Endometrial/Uterine Cancer	CCLE	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.6471
p.P551L	ACH-000954	Endometrial/Uterine Cancer	CCLE	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.6471
p.R852T	TCGA-AO-A0JE	BRCA	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.R852T	TCGA-XF-A9T8	BLCA	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.R852T	DO51927	BLCA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.R852T	DO3650	BRCA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.R556C	TCGA-AP-A051	UCEC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8301
p.R556C	DO42673	UCEC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8301
p.R556C	ACH-001610	Brain Cancer	CCLE	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8301
p.R629C	TCGA-AX-A2HD	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.8301
p.R629C	TCGA-CM-4751	COAD	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.8301
p.R629C	DO7866	COAD	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.8301
p.R629C	DO42608	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.8301
p.P624H	TCGA-BF-A1PZ	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.3056
p.P624H	DO50279	SKCM	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.3056
p.D841N	TCGA-BF-AAOX	SKCM	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.D841N	DO223907	SKCM	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.T627R	TCGA-CN-4727	HNSC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7876
p.T627R	DO14258	HNSC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7876
p.R853P	TCGA-CV-A461	HNSC	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.R853P	DO49058	HNSC	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.N631S	TCGA-DI-A1BU	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.2778
p.N631S	DO42023	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.2778
p.T626A	TCGA-DI-A1BU	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7139
p.T626A	DO42023	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7139
p.E847V	TCGA-DU-6392	LGG	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.7693
p.E847V	DO22237	LGG	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.7693
p.R556H	TCGA-DX-A6YS	SARC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8244
p.R556H	TCGA-EK-A2H0	CESC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8244
p.R556H	TCGA-MK-A4N7	THCA	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8244
p.R556H	DO49020	CESC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8244
p.R556H	DO220005	SARC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8244
p.R556H	DO39404	THCA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.8244
p.E857K	TCGA-EE-A2GC	SKCM	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1111
p.E857K	DO37839	SKCM	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1111
p.P628S	TCGA-EO-A22R	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.6752
p.P628S	DO42713	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.6752
p.P615H	TCGA-F5-6814	READ	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.0556
p.P615H	DO36556	READ	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.0556
p.E637Q	TCGA-FD-A3SS	BLCA	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.1111
p.E637Q	DO737	BLCA	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.1111
p.N622T	TCGA-FI-A2D5	UCEC	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.25
p.N622T	DO41331	UCEC	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.25
p.P628Q	TCGA-FS-A1ZG	SKCM	TCGA	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7035
p.P628Q	DO37523	SKCM	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7035
p.T554K	TCGA-L9-A7SV	LUAD	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7306
p.T554K	DO229025	LICA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7306
p.T554K	DO49875	LUAD	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7306
p.P683S	TCGA-MB-A8JK	SARC	TCGA	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation substituting flanking lysine	0.3333
p.P683S	DO220862	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation substituting flanking lysine	0.3333
p.P683S	DO220209	SARC	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation substituting flanking lysine	0.3333
p.A72V	TCGA-NH-A5IV	COAD	TCGA	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.0556
p.A72V	DO49095	COAD	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.0556
p.L546F	TCGA-NK-A5CR	LUSC	TCGA	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.1944
p.L546F	DO219207	LUSC	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.1944
p.A848V	TCGA-VS-A9UC	CESC	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.6936
p.A848V	DO219732	CESC	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.6936
p.A709T	TCGA-VS-A9UT	CESC	TCGA	APSSS	DEG_SPOP_SBC_1	696:700	Mutation blocking phosphorylation signal	0.5278
p.A709T	DO219740	CESC	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation blocking phosphorylation signal	0.5278
p.P844T	TCGA-WE-A8ZY	SKCM	TCGA	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.7031
p.P844T	DO51292	SKCM	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.7031
p.G705R	TCGA-WS-AB45	COAD	TCGA	APSSS	DEG_SPOP_SBC_1	696:700	Mutation rewiring degron network	0.1944
p.G705R	DO51734	COAD	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation rewiring degron network	0.1944
p.P77T	DO222990	BTCA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.P77T	DO230334	COCA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.P77T	SIDM01026	Esophageal Squamous Cell Carcinoma	GDSC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.P77T	KYSE-510	oesophagus	COSMIC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1944
p.A694V	DO227536	COCA	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation blocking phosphorylation signal	0.6944
p.A694V	DO227536	COCA	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation blocking phosphorylation signal	0.7222
p.A694V	DO220484	KICH	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation blocking phosphorylation signal	0.6944
p.A694V	DO220484	KICH	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation blocking phosphorylation signal	0.7222
p.A709P	DO229013	COCA	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation blocking phosphorylation signal	0.5278
p.D843N	DO50410	ESAD	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.3056
p.S696R	DO234461	ESAD	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation altering degron motif	0.7427
p.R853Q	DO233076	GACA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.V80M	DO233840	GACA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2778
p.E89A	DO233865	GACA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.25
p.D92E	DO228924	LICA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1667
p.P628T	DO228952	LICA	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7031
p.H566Q	DO228974	LICA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.0556
p.P855T	DO228976	LICA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1667
p.A848D	DO228978	LICA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation altering degron motif	0.7793
p.D841E	DO229028	LICA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.25
p.D83E	DO229032	LICA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation altering degron motif	0.5647
p.N560K	DO229035	LICA	ICGC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.2222
p.T627K	DO229037	LICA	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.7306
p.L636I	DO229009	LICA	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation substituting flanking lysine	0.25
p.L636I	ACH-000991	Colon/Colorectal Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation substituting flanking lysine	0.25
p.L636I	SNU-81	large intestine	COSMIC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation substituting flanking lysine	0.25
p.G95W	DO50937	LICA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.0833
p.S691I	DO23216	LINC	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation altering degron motif	0.7341
p.N622K	DO48732	LIRI	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.25
p.D88Y	DO231204	LUSC	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2778
p.R75Q	DO220886	MELA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1389
p.R75Q	DO229462	SKCA	ICGC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.1389
p.E850K	DO220895	MELA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.3056
p.D682N	DO222434	MELA	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation rewiring degron network	0.1944
p.E637K	DO229072	PRAD	ICGC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.1111
p.R678W	DO36285	PRAD	ICGC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation rewiring degron network	0.0833
p.R678W	ACH-001369	Ovarian Cancer	CCLE	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation rewiring degron network	0.0833
p.S699N	DO38404	STAD	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation altering degron motif	0.818
p.S707I	DO229211	THCA	ICGC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation rewiring degron network	0.1389
p.E840Q	DO229546	UTCA	ICGC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.A696V	SIDM02063	Colorectal Carcinoma	GDSC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation altering degron motif	0.5825
p.P630L	SIDM01966	Colorectal Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.3056
p.F78V	SIDM00545	Melanoma	GDSC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.F78V	ACH-000987	Skin Cancer	CCLE	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.F78V	Mewo	skin	COSMIC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.2222
p.P697S	SIDM00625	Other Sarcomas	GDSC	APSSS	DEG_SPOP_SBC_1	696:700	Mutation altering degron motif	0.5641
p.C550F	SIDM00427	Ewing's Sarcoma	GDSC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.3056
p.C550F	RH-1	soft tissue	COSMIC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.3056
p.E842D	SIDM01117	Small Cell Lung Carcinoma	GDSC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2778
p.E842D	NCI-H748	lung	COSMIC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2778
p.L638I	SIDM00193	Colorectal Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.0833
p.L638I	SNU-81	large intestine	COSMIC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.0833
p.S689N	SIDM00754	Non-Small Cell Lung Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation altering degron motif	0.818
p.R680W	SIDM00498	Colorectal Carcinoma	GDSC	PSSSS	DEG_SPOP_SBC_1	687:691	Mutation rewiring degron network	0.1389
p.G858W	SIDM01121	Small Cell Lung Carcinoma	GDSC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.0833
p.G858W	NCI-H69	lung	COSMIC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.0833
p.A542V	SIDM00534	Colorectal Carcinoma	GDSC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.0833
p.A542V	HT-115	large intestine	COSMIC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.0833
p.V87L	SIDM00980	Gastric Carcinoma	GDSC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.3056
p.V87L	ACH-000948	Gastric Cancer	CCLE	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.3056
p.V87L	23132-87	stomach	COSMIC	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.3056
p.R631H	SIDM01611	Endometrial Carcinoma	GDSC	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation rewiring degron network	0.2778
p.G856W	ACH-000358	Lung Cancer	CCLE	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1389
p.G856W	NCI-H69	lung	COSMIC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.1389
p.T859I	ACH-000995	Leukemia	CCLE	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.0556
p.T859I	Jurkat	haematopoietic and lymphoid tissue	COSMIC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.0556
p.R629H	ACH-000996	Endometrial/Uterine Cancer	CCLE	VPTTT	DEG_SPOP_SBC_1	625:629	Mutation altering degron motif	0.8244
p.A72D	ACH-001190	Skin Cancer	CCLE	ADSSS	DEG_SPOP_SBC_1	82:86	Mutation rewiring degron network	0.0556
p.P551T	ACH-001416	Bladder Cancer	CCLE	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation altering degron motif	0.7031
p.E840D	ACH-002176	Lung Cancer	CCLE	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.E840D	NCI-H748	lung	COSMIC	LDPFQE	LIG_APCC_ABBA_1	844:849	Mutation rewiring degron network	0.2222
p.C548F	ACH-002194	Bone Cancer	CCLE	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.25
p.C548F	RH-1	soft tissue	COSMIC	PTPGCT	DEG_SCF_FBW7_1	551:556	Mutation rewiring degron network	0.25

DegronMD: protein-targeted degradation, mutation and drug response to degrons

MYT1L

UniProt ID: Q9UL68

Entrez ID: 23040

Protein name: Myelin transcription factor 1-like protein (MyT1-L) (MyT1L)

External links: UniprotKB HGNC RefSeq COSMIC

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Kaplan plot for MYT1L in