DegronMD - Q9Y4K1(CRYBG1)

CRYBG1

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Mutation	Sample	Cancer	Dataset	Degron hit	Class	Location	Type	Impact score
p.L1051P	SIDM00672	Hepatocellular Carcinoma	GDSC	IEVFSD	LIG_APCC_ABBA_1	1037:1042	Mutation rewiring degron network	0.0833
p.L1051P	Hep_3B2_1-7	NS	COSMIC	IEVFSD	LIG_APCC_ABBA_1	1037:1042	Mutation rewiring degron network	0.0833
p.T820S	SIDM00477	Esophageal Carcinoma	GDSC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.25
p.T820S	OE33	oesophagus	COSMIC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.25
p.P809L	SIDM00927	Small Cell Lung Carcinoma	GDSC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.2222
p.P809L	NCI-H510A	lung	COSMIC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.2222
p.S803I	SIDM00217	Colorectal Carcinoma	GDSC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.0556
p.S803I	SNU-1040	large intestine	COSMIC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.0556
p.L804P	SNU-C5	large intestine	COSMIC	DKENR	DEG_APCC_KENBOX_2	813:817	Mutation rewiring degron network	0.0833
p.A861V	NCI-H1876	lung	COSMIC	AFSTS	DEG_SPOP_SBC_1	861:865	Mutation altering degron motif	0.5825

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*NOTE: the Kaplan plots were collected from OncoLnc