32,997 substructure mutations (Gatekeeper, G-loop, αC-helix, and A-loop) associated with drug-response in 547 human protein kinases using 5 large-scale cancer datasets are in our database.More>>
More than 679,000 Kinase mutation records were colloected from 5 large cancer genomics datasets: CCLE, GDSC, COSMIC, ICGC, and TCGA.More>>
Kinase substructure (Gatekeeper, G-loop, αC-helix, A-loop) positions in human kinome.Browse substructure
Mutations were colloected from 5 large cancer genomics datasets.Browse mutations
Kinase network-rewiring mutations (gain, loss, up-regulation and down-regulation) analysis.Network-rewiring mutations
Ruifeng Hu, Haodong Xu, Peilin Jia, Zhongming Zhao @ CPH, SBMI, UTHealth-Houston.
Ruifeng Hu, Haodong Xu, Peilin Jia, Zhongming Zhao, KinaseMD: kinase mutations and drug response database, Nucleic Acids Research, gkaa945, https://doi.org/10.1093/nar/gkaa945.