NME6
Entrez ID: 10201
Full name: NME/NM23 nucleoside diphosphate kinase 6
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: NDK
Chromosomal location: 3p21.31
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
Please click HERE
for better display.
NME6
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis....
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.
View more >>
GO - Biological processes (BP):
apoptotic process, CTP biosynthetic process, GTP biosynthetic process, negative regulation of cell growth, negative regulation of mitotic nuclear division, UTP biosynthetic process...
apoptotic process, CTP biosynthetic process, GTP biosynthetic process, negative regulation of cell growth, negative regulation of mitotic nuclear division, UTP biosynthetic process
View more >>
GO - Molecular function (MF):
ATP binding, metal ion binding, nucleoside diphosphate kinase activity...
ATP binding, metal ion binding, nucleoside diphosphate kinase activity
View more >>
GO - Cellular component (CC):
mitochondrion...
mitochondrion
View more >>
NME/NM23 nucleoside diphosphate kinase 6
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for NME6 in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc