MYLK3
Entrez ID: 91807
Full name: myosin light chain kinase 3
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CAMK: MLCK
Chromosomal location: 16q11.2
Substructure location: Gatekeeper: 589 A-loop: 655...677 G-loop: [N/A] αC-helix: [N/A]
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MYLK3
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity)....
Kinase that phosphorylates MYL2 in vitro. Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility (By similarity).
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GO - Biological processes (BP):
cardiac myofibril assembly, cellular response to interleukin-1, positive regulation of sarcomere organization, protein phosphorylation, regulation of vascular permeability involved in acute inflammatory response, sarcomere organization, sarcomerogenesis...
cardiac myofibril assembly, cellular response to interleukin-1, positive regulation of sarcomere organization, protein phosphorylation, regulation of vascular permeability involved in acute inflammatory response, sarcomere organization, sarcomerogenesis
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GO - Molecular function (MF):
ATP binding, calmodulin-dependent protein kinase activity, myosin light chain kinase activity...
ATP binding, calmodulin-dependent protein kinase activity, myosin light chain kinase activity
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GO - Cellular component (CC):
actin cytoskeleton, cytosol, cytoplasm...
actin cytoskeleton, cytosol, cytoplasm
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myosin light chain kinase 3
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αC-helix
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αC-helix
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Minimum 5 samples
Minimum 10 samples
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Kaplan plot for MYLK3 in
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*NOTE: the Kaplan plots were collected from OncoLnc