NEK10
Entrez ID: 152110
Full name: NIMA related kinase 10
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: NEK: NEK10
Chromosomal location: 3p24.1
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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NEK10
Plays a role in the cellular response to UV irradiation. Mediates G2/M cell cycle arrest, MEK autoactivation and ERK1/2-signaling pathway activation in response to UV irradiation....
Plays a role in the cellular response to UV irradiation. Mediates G2/M cell cycle arrest, MEK autoactivation and ERK1/2-signaling pathway activation in response to UV irradiation.
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GO - Biological processes (BP):
positive regulation of MAP kinase activity, positive regulation of protein autophosphorylation, protein phosphorylation, regulation of cell cycle G2/M phase transition, regulation of ERK1 and ERK2 cascade...
positive regulation of MAP kinase activity, positive regulation of protein autophosphorylation, protein phosphorylation, regulation of cell cycle G2/M phase transition, regulation of ERK1 and ERK2 cascade
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GO - Molecular function (MF):
ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity...
ATP binding, metal ion binding, protein kinase activity, protein serine/threonine kinase activity
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GO - Cellular component (CC):
protein kinase complex...
protein kinase complex
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NIMA related kinase 10
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Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
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Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
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Kaplan plot for NEK10 in
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*NOTE: the Kaplan plots were collected from OncoLnc