ALPK2
Entrez ID: 115701
Full name: alpha kinase 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Atypical: Alpha: Alpha-Unclassified
Chromosomal location: 18q21.31-q21.32
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
Please click HERE
for better display.
ALPK2
Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752)....
Protein kinase that recognizes phosphorylation sites in which the surrounding peptides have an alpha-helical conformation (PubMed:10021370). Regulates cardiac development and cardiomyocyte differentiation by negatively regulating Wnt/beta-catenin signaling (PubMed:29888752).
View more >>
GO - Biological processes (BP):
cardiac muscle cell development, epicardium morphogenesis, establishment of cell polarity, heart morphogenesis, negative regulation of Wnt signaling pathway involved in heart development, regulation of apoptotic process, regulation of gene expression...
cardiac muscle cell development, epicardium morphogenesis, establishment of cell polarity, heart morphogenesis, negative regulation of Wnt signaling pathway involved in heart development, regulation of apoptotic process, regulation of gene expression
View more >>
GO - Molecular function (MF):
ATP binding, protein serine/threonine kinase activity...
ATP binding, protein serine/threonine kinase activity
View more >>
GO - Cellular component (CC):
basolateral plasma membrane...
basolateral plasma membrane
View more >>
alpha kinase 2
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for ALPK2 in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc