VRK3
Entrez ID: 51231
Full name: VRK serine/threonine kinase 3
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CK1: VRK
Chromosomal location: 19q13.33
Substructure location: Gatekeeper: 259 A-loop: [N/A] G-loop: [N/A] αC-helix: 211...221
Please click HERE
for better display.
VRK3
Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus....
Inactive kinase that suppresses ERK activity by promoting phosphatase activity of DUSP3 which specifically dephosphorylates and inactivates ERK in the nucleus.
View more >>
GO - Biological processes (BP):
negative regulation of ERK1 and ERK2 cascade, peptidyl-serine phosphorylation, positive regulation of phosphoprotein phosphatase activity, Wnt signaling pathway...
negative regulation of ERK1 and ERK2 cascade, peptidyl-serine phosphorylation, positive regulation of phosphoprotein phosphatase activity, Wnt signaling pathway
View more >>
GO - Molecular function (MF):
ATP binding, protein phosphatase binding, protein serine/threonine kinase activity...
ATP binding, protein phosphatase binding, protein serine/threonine kinase activity
View more >>
GO - Cellular component (CC):
nucleolus, nucleoplasm, nucleus, cytoplasm, intracellular membrane-bounded organelle...
nucleolus, nucleoplasm, nucleus, cytoplasm, intracellular membrane-bounded organelle
View more >>
VRK serine/threonine kinase 3
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for VRK3 in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc