CDK20
Entrez ID: 23552
Full name: cyclin dependent kinase 20
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CMGC: CDK: CCRK
Chromosomal location: 9q22.1
Substructure location: Gatekeeper: 81 A-loop: 144...155, 160...168 G-loop: [N/A] αC-helix: [N/A]
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CDK20
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell...
Required for high-level Shh responses in the developing neural tube. Together with TBC1D32, controls the structure of the primary cilium by coordinating assembly of the ciliary membrane and axoneme, allowing GLI2 to be properly activated in response to SHH signaling (By similarity). Involved in cell growth. Activates CDK2, a kinase involved in the control of the cell cycle, by phosphorylating residue 'Thr-160'.
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GO - Biological processes (BP):
cell cycle, cell division, multicellular organism development, protein phosphorylation...
cell cycle, cell division, multicellular organism development, protein phosphorylation
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GO - Molecular function (MF):
ATP binding, cyclin-dependent protein serine/threonine kinase activity...
ATP binding, cyclin-dependent protein serine/threonine kinase activity
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GO - Cellular component (CC):
nucleoplasm, nucleus, cilium, cytoplasm...
nucleoplasm, nucleus, cilium, cytoplasm
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cyclin dependent kinase 20
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*NOTE: the Kaplan plots were collected from OncoLnc