SCYL1
Entrez ID: 57410
Full name: SCY1 like pseudokinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: SCY1
Chromosomal location: 11q13.1
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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SCYL1
Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903). Has no detectable kinase activity in vitro (PubMed:18556652)....
Regulates COPI-mediated retrograde protein traffic at the interface between the Golgi apparatus and the endoplasmic reticulum (PubMed:18556652). Involved in the maintenance of the Golgi apparatus morphology (PubMed:26581903). Has no detectable kinase activity in vitro (PubMed:18556652).
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GO - Biological processes (BP):
cellular protein localization, inflammatory response, neuron development, retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, spinal cord motor neuron differentiation...
cellular protein localization, inflammatory response, neuron development, retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum, spinal cord motor neuron differentiation
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GO - Molecular function (MF):
ATP binding, cadherin binding, DNA binding, protein tyrosine kinase activity...
ATP binding, cadherin binding, DNA binding, protein tyrosine kinase activity
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GO - Cellular component (CC):
microtubule organizing center, cytosol, cis-Golgi network, COPI vesicle coat, Golgi apparatus, nucleus, cytoplasm, endoplasmic reticulum-Golgi intermediate compartment, membrane...
microtubule organizing center, cytosol, cis-Golgi network, COPI vesicle coat, Golgi apparatus, nucleus, cytoplasm, endoplasmic reticulum-Golgi intermediate compartment, membrane
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SCY1 like pseudokinase 1
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*NOTE: the Kaplan plots were collected from OncoLnc