FAM20A
Entrez ID: 54757
Full name: FAM20A golgi associated secretory pathway pseudokinase
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: PKL: FJ
Chromosomal location: 17q24.2
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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FAM20A
Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the ...
Pseudokinase that acts as an allosteric activator of the Golgi serine/threonine protein kinase FAM20C and is involved in biomineralization of teeth. Forms a complex with FAM20C and increases the ability of FAM20C to phosphorylate the proteins that form the 'matrix' that guides the deposition of the enamel minerals.
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GO - Biological processes (BP):
biomineral tissue development, calcium ion homeostasis, enamel mineralization, positive regulation of protein phosphorylation, protein phosphorylation, response to bacterium, tooth eruption...
biomineral tissue development, calcium ion homeostasis, enamel mineralization, positive regulation of protein phosphorylation, protein phosphorylation, response to bacterium, tooth eruption
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GO - Molecular function (MF):
protein serine/threonine kinase activator activity...
protein serine/threonine kinase activator activity
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GO - Cellular component (CC):
endoplasmic reticulum, extracellular exosome, extracellular space, Golgi apparatus, cell...
endoplasmic reticulum, extracellular exosome, extracellular space, Golgi apparatus, cell
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FAM20A golgi associated secretory pathway pseudokinase
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A-loop
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αC-helix
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Kaplan plot for FAM20A in
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*NOTE: the Kaplan plots were collected from OncoLnc