MYLK2
Entrez ID: 85366
Full name: myosin light chain kinase 2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CAMK: MLCK
Chromosomal location: 20q11.21
Substructure location: Gatekeeper: 359 A-loop: 425...447 G-loop: [N/A] αC-helix: [N/A]
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MYLK2
Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain....
Implicated in the level of global muscle contraction and cardiac function. Phosphorylates a specific serine in the N-terminus of a myosin light chain.
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GO - Biological processes (BP):
cardiac muscle contraction, cardiac muscle tissue morphogenesis, neuromuscular synaptic transmission, peptidyl-threonine phosphorylation, positive regulation of gene expression, protein autophosphorylation, regulation of muscle filament sliding, skeletal muscle cell differentiation, skeletal muscle ...
cardiac muscle contraction, cardiac muscle tissue morphogenesis, neuromuscular synaptic transmission, peptidyl-threonine phosphorylation, positive regulation of gene expression, protein autophosphorylation, regulation of muscle filament sliding, skeletal muscle cell differentiation, skeletal muscle satellite cell differentiation, striated muscle contraction
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GO - Molecular function (MF):
ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, myosin light chain binding, myosin light chain kinase activity...
ATP binding, calmodulin binding, calmodulin-dependent protein kinase activity, myosin light chain binding, myosin light chain kinase activity
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GO - Cellular component (CC):
nucleus, cytoplasm, sarcomere, synapse...
nucleus, cytoplasm, sarcomere, synapse
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myosin light chain kinase 2
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Kaplan plot for MYLK2 in
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*NOTE: the Kaplan plots were collected from OncoLnc