PEAK1
Entrez ID: 79834
Full name: pseudopodium enriched atypical kinase 1
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: Other: NKF3
Chromosomal location: 15q24.3
Substructure location: Gatekeeper: A-loop: G-loop: αC-helix:
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PEAK1
Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:23105102, PubMed:20534451). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654)....
Probable catalytically inactive kinase. Scaffolding protein that regulates the cytoskeleton to control cell spreading and migration by modulating focal adhesion dynamics (PubMed:23105102, PubMed:20534451). Acts as a scaffold for mediating EGFR signaling (PubMed:23846654).
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GO - Biological processes (BP):
cell migration, focal adhesion assembly, protein autophosphorylation, protein phosphorylation, regulation of focal adhesion assembly, substrate adhesion-dependent cell spreading...
cell migration, focal adhesion assembly, protein autophosphorylation, protein phosphorylation, regulation of focal adhesion assembly, substrate adhesion-dependent cell spreading
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GO - Molecular function (MF):
identical protein binding, non-membrane spanning protein tyrosine kinase activity, protein kinase activity...
identical protein binding, non-membrane spanning protein tyrosine kinase activity, protein kinase activity
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GO - Cellular component (CC):
actin cytoskeleton, cytoplasm, focal adhesion...
actin cytoskeleton, cytoplasm, focal adhesion
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pseudopodium enriched atypical kinase 1
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αC-helix
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G-loop
αC-helix
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Minimum 10 samples
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Kaplan plot for PEAK1 in
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*NOTE: the Kaplan plots were collected from OncoLnc