RPS6KB2
Entrez ID: 6199
Full name: ribosomal protein S6 kinase B2
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: AGC: RSK: RSKp70
Chromosomal location: 11q13.2
Substructure location: Gatekeeper: 148 A-loop: 211...234 G-loop: [N/A] αC-helix: [N/A]
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RPS6KB2
Phosphorylates specifically ribosomal protein S6 (PubMed:29750193). Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193)....
Phosphorylates specifically ribosomal protein S6 (PubMed:29750193). Seems to act downstream of mTOR signaling in response to growth factors and nutrients to promote cell proliferation, cell growth and cell cycle progression in an alternative pathway regulated by MEAK7 (PubMed:29750193).
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GO - Biological processes (BP):
intracellular signal transduction, positive regulation of translational initiation, protein kinase B signaling, protein phosphorylation, signal transduction, TOR signaling, translation...
intracellular signal transduction, positive regulation of translational initiation, protein kinase B signaling, protein phosphorylation, signal transduction, TOR signaling, translation
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GO - Molecular function (MF):
ATP binding, peptide binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity...
ATP binding, peptide binding, protein kinase activity, protein serine/threonine kinase activity, ribosomal protein S6 kinase activity
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GO - Cellular component (CC):
nucleoplasm, nucleus, cytoplasm...
nucleoplasm, nucleus, cytoplasm
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ribosomal protein S6 kinase B2
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Kaplan plot for RPS6KB2 in
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*NOTE: the Kaplan plots were collected from OncoLnc