CDK11A
Entrez ID: 728642
Full name: cyclin dependent kinase 11A
External links: HGNC UniprotKB Ensembl RefSeq COSMIC
Family: CMGC: CDK: CDK11
Chromosomal location: 1p36.33
Substructure location: Gatekeeper: 504 A-loop: 567...578, 580...590 G-loop: [N/A] αC-helix: [N/A]
Please click HERE
for better display.
CDK11A
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression....
Appears to play multiple roles in cell cycle progression, cytokinesis and apoptosis. The p110 isoforms have been suggested to be involved in pre-mRNA splicing, potentially by phosphorylating the splicing protein SFRS7. The p58 isoform may act as a negative regulator of normal cell cycle progression.
View more >>
GO - Biological processes (BP):
apoptotic process, mitotic cell cycle, protein phosphorylation, regulation of cell growth, regulation of gene expression, regulation of mitotic cell cycle, regulation of mRNA processing, regulation of transcription, DNA-templated...
apoptotic process, mitotic cell cycle, protein phosphorylation, regulation of cell growth, regulation of gene expression, regulation of mitotic cell cycle, regulation of mRNA processing, regulation of transcription, DNA-templated
View more >>
GO - Molecular function (MF):
ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity...
ATP binding, cyclin-dependent protein serine/threonine kinase activity, protein kinase activity, protein serine/threonine kinase activity
View more >>
GO - Cellular component (CC):
nucleus, cytoplasm...
nucleus, cytoplasm
View more >>
cyclin dependent kinase 11A
Control panel
Show dataset:
Show substructure:
All sites
Gatekeeper
A-loop
G-loop
αC-helix
Gatekeeper
A-loop
G-loop
αC-helix
Filter mutation sites
All sites
Minimum 5 samples
Minimum 10 samples
Minimum 5 samples
Minimum 10 samples
Data table is loading....
Kaplan plot for CDK11A in
Download patient group data (Lower:Upper = 50%:50%)
*NOTE: the Kaplan plots were collected from OncoLnc