| Tag | Content |
|---|---|
| Uniprot ID | A0A0G2K475 |
| Entrez ID | 360588 |
| Genbank protein ID | |
| Genbank nucleotide ID | XM_001081096.5; XM_340869.5; XM_006247063.3; XM_008768157.1; |
| Ensembl protein ID | ENSRNOP00000072934 |
| Ensembl nucleotide ID | ENSRNOG00000059997 |
| Gene name | BRCA1-interacting protein C-terminal helicase 1 |
| Gene symbol | Brip1 |
| Organism | Rattus norvegicus |
| NCBI taxa ID | 10116 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSVLSEYTI GGVKIHFPCR AYPAQLAMMN SIVRGLNSSQ HCLLESPTGS GKSLALLCSA 60 LAWQQSLTGK PVDEGLNKKP EAPSSCSCSC HSKNFTYSDT NLDTSPHFSS PSKPSSERNA 120 VSSPCRDSPE RNSLAAKLSA KKHASIHEDD DFQVEKKRIR PLETTQQIRK RHCLEKDVHH 180 LDARLASEKR VKPESPIRKT SSSFQNPDGL CSRCCCSANQ GINKESANTV KKDNGDQSKR 240 PKIYFGTRTH KQIAQITREL RKTAYSGVPM TILSSRDHTC VHPEVVGNFN RNEKCMELLD 300 GKHGKSCYFY HGVHRISNQQ TLQFLHGISK AWDIEELVSL GRKLKACPYY TARELIDSAD 360 IIFCPYNYLL DSQIRESMDI KLKEQVVILD EAHNIEECAR ETASYSVTEV QLRFARDELD 420 SLINSNIRKK SHEPLRDVCY NLINWLETNS KNLVERDYES SCKIWSGNEM LLNLHRMGIT 480 AASFPVLQKH LSAVLQKEEK VTSTHGKEEA IQIPIISAST QIMLKGLFMV LDYLFRKNSR 540 FADDYKVAIQ QTYSWTNQIA IFDKNALLPV PKNKKHSRQK IGVNVLNFWC LNPAVAFSDI 600 NDKVRTIVLT SGTLSPLKSF SSELGVTFNI QLEANHVISN SQVWVGTVGS GPKGRNLCAT 660 FQHTETFEFQ DEVGMLLLSV CQTVSQGILC FLPSYKLLEK LRERWIFTGL WHSLESVKTV 720 IAEPQGGEKT DFDELLQVYY DAIKFKGEKD GALLIAVCRG KVSEGLDFSD DNARAVITIG 780 IPFPNVKDLQ VELKRQYNDH HSKLRGLLPG RQWYEIQAYR ALNQALGRCI RHKNDWGALI 840 LVDDRFNNNP DRYISGLSKW VRQQIQHHST FASALESLTE FSKRHQKVTN RSKKEEKCTK 900 ENGSTLDVAC LEGSTLTSVS EASHQTPENS LEEEAKVCVQ EQRYPQMAAE NPSGPSHGVS 960 RRKESDPGLR EKSVQTMKTE KSEISRSSSP TFGKQTEPVN WPIFNSLKRH FNSKVKNRTP 1020 VLKSSKNHAS ASSAFNKTAL PLTGKCVSSS APANTPLAPC PQSEVIIPSV KADTTPAKTH 1080 CKQNEKDPSP DAELSPVTEE AKGSSSNPAV GTEVDDDSVC FTPELFDPVS TDEENSELVE 1140 TDRSSNNSDC LSAEELFETV TGFGQK 1166 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BRIP1 | A0A452EU29 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BRIP1 | 83990 | Q9BX63 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Brip1 | 237911 | Q5SXJ3 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BRIP1 | 454796 | H2QDL5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Brip1 | 360588 | A0A0G2K475 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | brip1 | 794038 | B7ZDD5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0031965 | nuclear membrane |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0003682 | chromatin binding |
| GO:0003677 | DNA binding |
| GO:0003678 | DNA helicase activity |
| GO:1904385 | cellular response to angiotensin |
| GO:0071456 | cellular response to hypoxia |
| GO:0071295 | cellular response to vitamin |
| GO:0051026 | chiasma assembly |
| GO:1990918 | double-strand break repair involved in meiotic recombination |
| GO:0008584 | male gonad development |
| GO:0010705 | meiotic DNA double-strand break processing involved in reciprocal meiotic recombination |
| GO:0008285 | negative regulation of cell population proliferation |
| GO:0010629 | negative regulation of gene expression |
| GO:0006289 | nucleotide-excision repair |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0009636 | response to toxic substance |
| GO:0072520 | seminiferous tubule development |
| GO:0007286 | spermatid development |
| GO:0007283 | spermatogenesis |
| GO:0007284 | spermatogonial cell division |
| GO:0007129 | synapsis |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51193 | HELICASE_ATP_BIND_2 |