| Tag | Content |
|---|---|
| Uniprot ID | H2QDL5; A0A2J8JD20; |
| Entrez ID | 454796 |
| Genbank protein ID | JAA34636.1; JAA16842.1; JAA30376.1; JAA08857.1; |
| Genbank nucleotide ID | XM_009433004.2; XM_511607.5; |
| Ensembl protein ID | ENSPTRP00000016108 |
| Ensembl nucleotide ID | ENSPTRG00000009493 |
| Gene name | BRCA1 interacting protein C-terminal helicase 1 |
| Gene symbol | BRIP1 |
| Organism | Pan troglodytes |
| NCBI taxa ID | 9598 |
| Cleft type | |
| Developmental stage | |
| Data sources | Homology search |
| Reference | |
| Functional description | |
| Sequence | MSSMWSEYTI GGVKIYFPYK AYPSQLAMMN SILRGLNSKQ HCLLESPTGS GKSLALLCSA 60 LAWQQSLSGK PADEGVSEKA EVQLSCCCAC HSKDFTNNDM NQGTSRHFNY PSTPPSERNG 120 TSSTCQDSPE KTTLAAKLSA KKQASIYRDE NDDFQVEKKR IRPLETTQQI RKRHCFGTEV 180 HNLDAKVDSG KTVKLNSPLE KINSFSPQKP PGHCSRCCCS TKQGNSQESS NTIKKDHTGK 240 SKIPKIYFGT RTHKQIAQIT RELRRTAYSG VPMTILSSRD HTCVHPEVVG NFNRNEKCME 300 LLDGKNGKSC YFYHGVHKIS DQHTLQTFQG MCKAWDIEEL VSLGKKLKSC PYYTARELIQ 360 DADIIFCPYN YLLDAQIRES MDLNLKEQVV ILDEAHNIED CARESASYSV TEVQLRFARD 420 ELDSMVNNNI RKKDHEPLRA VCCSLINWLE ANAEYLVERD YESACKIWSG NEMLLTLHKM 480 GITTATFPIL QGHFSAVLQK EEKISPIYGK EEAREVPVIS ASTQIMLKGL FMVLDYLFRQ 540 NSRFADDYKI AIQQTYSWTN QIDISDKNGL LVLPKNKKRS RQKTAVHVLN FWCLNPAVAF 600 SDINGKVQTI VLTSGTLSPM KSFSSELGVT FTIQLEANHI IKNSQVWVGT IGSGPKGRNL 660 CATFQNTETF EFQDEVGALL LSVCQTVSQG ILCFLPSYKL LEKLKERWLS TGLWHNLELV 720 KTVIVEPQGG EKTNFDELLQ VYYDAIKYKG EKDGALLVAV CRGKVSEGLD FSDDNARAVI 780 TIGIPFPNVK DLQVELKRQY NDHHSKLRGL LPGRQWYEIQ AYRALNQALG RCIRHRNDWG 840 ALILVDDRFR NNPSRYISGL SKWVRQQIQH HSTFESALES LAEFSKKHQK VLNVSIKDRT 900 NIQDNESTLE MTSLKYSTPP YLLEAASHLS PENFVEDEAK ICVQELQCPK IITKNSPLPS 960 SIISRKEKND PVFLEEAGKA EKIVISRSTS PTFNKQTKRV SWSSFNSLGQ YFTGKIPKAT 1020 PELRSSENSA SSPPRFKTEK MESKTVLPFT DKCESSNLTV NTSFGSCPQS ETIISSLKID 1080 ATLTRKNHSE HPLCSEEALD PDIELSLVSE EDKQSTSNRD FETEAEDESI YFTPELYDPE 1140 DTDEEKNDLA ETDRGNRLAN NSDCILAKDL FEIRTIKEVD SAREVKAEDC IDTKLNGILH 1200 IEESKIDDID GNVKTTWIKE LELGKTHEIE IKNFKPSPSK NKGMFPGFK 1249 |
Abbreviation :
CLO : cleft lip only. CPO : cleft palate only.
CLP : cleft lip and palate. CL/P : cleft lip with/without cleft palate.
For humans: CL/P, CLO, CPO, and CLP. For mice: CLO, CLP, and CPO.
| Relation | Gene symbol | Entrez ID | UniProt ID | Cleft type | Developmental stage | Species | Evidence | Details |
|---|---|---|---|---|---|---|---|---|
| 1:1 ortholog | BRIP1 | A0A452EU29 | Capra hircus | Prediction | More>> | |||
| 1:1 ortholog | BRIP1 | 83990 | Q9BX63 | Homo sapiens | Publication | More>> | ||
| 1:1 ortholog | Brip1 | 237911 | Q5SXJ3 | Mus musculus | Prediction | More>> | ||
| 1:1 ortholog | BRIP1 | 454796 | H2QDL5 | Pan troglodytes | Prediction | More>> | ||
| 1:1 ortholog | Brip1 | 360588 | A0A0G2K475 | Rattus norvegicus | Prediction | More>> | ||
| 1:1 ortholog | brip1 | 794038 | B7ZDD5 | Danio rerio | Prediction | More>> |
| GO ID | GO Term |
|---|---|
| GO:0005737 | cytoplasm |
| GO:0031965 | nuclear membrane |
| GO:0005654 | nucleoplasm |
| GO:0005634 | nucleus |
| GO:0005524 | ATP binding |
| GO:0003677 | DNA binding |
| GO:0003678 | DNA helicase activity |
| GO:0051026 | chiasma assembly |
| GO:1990918 | double-strand break repair involved in meiotic recombination |
| GO:0010705 | meiotic DNA double-strand break processing involved in reciprocal meiotic recombination |
| GO:0006289 | nucleotide-excision repair |
| GO:0006357 | regulation of transcription by RNA polymerase II |
| GO:0072520 | seminiferous tubule development |
| GO:0007286 | spermatid development |
| GO:0007284 | spermatogonial cell division |
| PROSITE ID | PROSITE Term |
|---|---|
| PS51193 | HELICASE_ATP_BIND_2 |